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Record W2971428495 · doi:10.1038/s41398-019-0592-5

Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer’s disease

2019· article· en· W2971428495 on OpenAlexfundno aff
Byron Creese, Evangelos Vassos, Sverre Bergh, Lavinia Athanasiu, Iskandar Johar, Arvid Rongve, Ingrid Tøndel Medbøen, Miguel Vasconcelos Da Silva, Eivind Aakhus, Fred Andersen, Francesco Bettella, Anne Brækhus, Srdjan Djurovic, Giulia Paroni, Petroula Proitsi, Ingvild Saltvedt, Davide Seripa, Eystein Stordal, Tormod Fladby, Dag Aarsland, Ole A. Andreassen, Clive Ballard, Geir Selbæk

Bibliographic record

VenueTranslational Psychiatry · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Associations and Epidemiology
Canadian institutionsnot available
FundersNorwegian Institute of Public HealthNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchNational Institutes of HealthHelse Sør-Øst RHFIXICOGenentechSykehuset Innlandet HFH. Lundbeck A/SServierKing's College LondonUniversity of ExeterMeso Scale DiagnosticsDepartment of Health and Social CareNational Institute on AgingNational Institute for Health and Care ResearchNorthern California Institute for Research and EducationEisaiSouth London and Maudsley NHS Foundation TrustNorges Teknisk-Naturvitenskapelige UniversitetUniversity of PennsylvaniaUniversity of Southern CaliforniaPfizerBioClinicaBiogenU.S. Department of DefenseEli Lilly and CompanyBristol-Myers SquibbAlzheimer's Disease Neuroimaging InitiativeMinistero della SaluteNovartis Pharmaceuticals CorporationAlzheimer's Association
KeywordsSchizophrenia (object-oriented programming)PsychosisPsychiatryDiseasePsychologyCohortGenome-wide association studyMedicineClinical psychologyInternal medicineSingle-nucleotide polymorphismGenotype

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.388

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.277
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations51
Published2019
Admission routes1
Has abstractyes

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