Instrumentation for high-dose, high-resolution dosimetry for microbeam radiation therapy using samarium-doped fluoroaluminate and fluorophosphate glass plates
Why this work is in the frame
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Bibliographic record
Abstract
Abstract We show that 1% Sm-doped fluoroaluminate (FA) glass plate and a suitably modified fluorescence confocal microscope provide an excellent radiation detection platform for high-dose measurements at high resolution down to the micron scale. We have used a custom-modified fluoroscopic confocal microscope apparatus to scan, separate, detect, and digitize the photoluminescence (PL) signals from Sm 3+ and Sm 2+ ions in both FA and fluorophosphate (FP) glasses within a selected focal depth of the microscope below the sample surface. The response ( R ) of Sm-doped FA and FP glass plates to incident x-ray radiation was studied in detail in which R was defined as the difference in the ratio of PL signals from Sm 2+ and Sm 3+ before and after irradiation. We report on a number of important issues related to the use of these Sm-doped FA and FP glass plates in microbeam radiation therapy (MRT) dosimetry: The dependence of the Sm 3+ to Sm 2+ conversion, and hence R on the dose rate over some four orders of magnitude; the energy dependence of R at a given dose rate for both FA and FP samples with various concentrations of Sm 3+ doping; R versus dose behavior at different energies up to 2000 Gy air and the derivation of the detector calibration curves; the stability of the Sm-doped plates after they have been exposed; the instrumental limits of the present measurement technique.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it