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Record W2976599382 · doi:10.1136/gutjnl-2019-319548

International consensus conference on stool banking for faecal microbiota transplantation in clinical practice

2019· review· en· W2976599382 on OpenAlexaff
Giovanni Cammarota, Gianluca Ianiro, Colleen Kelly, Benjamin H. Mullish, Jessica R. Allegretti, Zain Kassam, Lorenza Putignani, Monika Fischer, Josbert J. Keller, Samuel P. Costello, Harry Sokol, Patrizia Kump, Reetta Satokari, Stacy A. Kahn, Dina Kao, Perttu Arkkila, Ed J. Kuijper, Maria J. G. T. Vehreschild, C. Pintus, Loris Riccardo Lopetuso, Luca Masucci, Franco Scaldaferri, Elisabeth M. Terveer, Max Nieuwdorp, Antonio López–Sanromán, Juozas Kupčinskas, Ailsa Hart, Herbert Tilg, Antonio Gasbarrini

Bibliographic record

VenueGut · 2019
Typereview
Languageen
FieldMedicine
TopicClostridium difficile and Clostridium perfringens research
Canadian institutionsCanadian Association of GastroenterologyUniversity of Alberta
Fundersnot available
KeywordsFecal bacteriotherapyMedicineClostridium difficileDelphi methodEconomic shortageClinical PracticeBest practiceClostridioidesPatient safetyBusinessIntensive care medicineHealth carePublic relationsPolitical scienceFamily medicineInternal medicineComputer science

Abstract

fetched live from OpenAlex

infection (CDI), its widespread dissemination is limited by several obstacles, including lack of dedicated centres, difficulties with donor recruitment and complexities related to regulation and safety monitoring. Given the considerable burden of CDI on global healthcare systems, FMT should be widely available to most centres.Stool banks may guarantee reliable, timely and equitable access to FMT for patients and a traceable workflow that ensures safety and quality of procedures. In this consensus project, FMT experts from Europe, North America and Australia gathered and released statements on the following issues related to the stool banking: general principles, objectives and organisation of the stool bank; selection and screening of donors; collection, preparation and storage of faeces; services and clients; registries, monitoring of outcomes and ethical issues; and the evolving role of FMT in clinical practice,Consensus on each statement was achieved through a Delphi process and then in a plenary face-to-face meeting. For each key issue, the best available evidence was assessed, with the aim of providing guidance for the development of stool banks in order to promote accessibility to FMT in clinical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.047
metaresearch head score (Gemma)0.054
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.047
Threshold uncertainty score0.250

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0470.054
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.007
Bibliometrics0.0060.005
Science and technology studies0.0010.002
Scholarly communication0.0040.003
Open science0.0060.006
Research integrity0.0070.007
Insufficient payload (model declined to judge)0.0100.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.231
GPT teacher head0.493
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations485
Published2019
Admission routes1
Has abstractyes

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