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Record W2978672514 · doi:10.1002/uog.20707

OP07.01: New sonographic classification of adenomyosis: do type and degree of adenomyosis correlate to severity of symptoms?

2019· article· en· W2978672514 on OpenAlexaboutno aff
Lucia Lazzeri, C. Exacoustós, G. Morosetti, Francesca Conway, S. Camilli, Francesco Giuseppe Martire, Giorgia Monti, Emilio Piccione, Errico Zupi

Bibliographic record

VenueUltrasound in Obstetrics and Gynecology · 2019
Typearticle
Languageen
FieldMedicine
TopicEndometriosis Research and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsAdenomyosisMedicineEndometriosisInfertilityGynecologyObstetricsVisual analogue scalePregnancySurgery

Abstract

fetched live from OpenAlex

To correlate type and degree of adenomyosis, scored through a new system based on transvaginal sonographic (TVS) features, to patient's symptoms and fertility. This is a multicentre, prospective study performed in two Endometriosis tertiary referral centre (Canadian Task Force II-2) including 108 patients with ultrasound diagnosis of adenomyosis and 40 controls without any sonographic signs of myometrial pathologies. A new ultrasonographic scoring system designed to assess the severity and the extension of uterine adenomyosis was used to stage the disease in correlation with clinical symptoms. Menstrual uterine bleeding was assessed by a pictorial blood loss analysis chart (PBAC), painful symptoms were evaluated using a visual analogue scale (VAS) and infertility factors were considered. 108 patients with adenomyosis (mean age 37.7±7.7 yrs) were classified according to the proposed scoring system. The 22 patients with a score of focal-mild adenomyosis were younger compared to the patients with severe disease and showed a higher percentage (75.86%) of severe dysmenorrhea (VAS>5) and infertility (24.13%). The 20 patients with severe-diffuse adenomyosis, according to the score, showed in 95.24% of cases heavy menstrual bleeding (PBAC>100) and in 80.95% severe dysmenorrhea. All the 21 patients with adenomyomas had a PBAC>100. The evaluation of the extension of adenomyosis in the myometrium and in the JZ seems important in correlation to the severity of symptoms and infertility, as well as for an emerging request of surgical treatment. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.027
Threshold uncertainty score0.054

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.285
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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