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Record W2980858782 · doi:10.1016/j.jalz.2019.06.871

P1‐316: THE CLINICAL CHARACTERISTICS OF COGNITIVE IMPAIRMENT IN PATIENTS WITH VASCULAR MILD COGNITIVE IMPAIRMENT

2019· article· en· W2980858782 on OpenAlexaboutno aff
Junliang Yuan

Bibliographic record

VenueAlzheimer s & Dementia · 2019
Typearticle
Languageen
FieldMedicine
TopicCerebrovascular and Carotid Artery Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsMontreal Cognitive AssessmentAtrophyTemporal lobeCognitive impairmentNeuropsychologyMedicineInternal medicineCognitionPsychologyFrontal lobeWhite matterAudiologyCardiologyPsychiatryMagnetic resonance imagingRadiologyEpilepsy

Abstract

fetched live from OpenAlex

To investigate the characteristics of the cognitive impairment in patients with vascular mild cognitive impairment (VaMCI). Seventy-five patients with VaMCI and 38 age, gender-matched healthy subjects were recruited from the department of Neurology, Beijing Chaoyang Hospital, Capital Medical University between Jan 2016 and June 2016. All the participant underwent the neuropsychological tests. The Fazekas scale was used to assess the severity of white matter lesions, and the medial temporal lobe atrophy (MTA) to evaluate the atrophic severity of medial temporal lobe. The results of our study showed that patients with VaMCI were associated with comprehensive cognitive function deficits, including MMSE [25.7±2.3 vs 28.4±2.0] MoCA [22.8±3.9 vs 26.3±3.7], AVLD-I [5.1±1.0 vs 8.9±1.9], AVLT-D [3.7±1.0 vs 9.8±1.5] and AVLT-R [7.6±1.9 vs 12±1.5] (P<0.05) . Correlation analysis showed that the scale of medial temporal lobe atrophy had a negative relationship with the performance of MoCA (r=−0.434, P=0.002). Our findings demonstrate patients with VaMCI were closely correlated to cognitive impairment, especially with memory decline, which may be attributed to white matter lesions and the atrophy of medial temporal lobe.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.271
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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