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Record W2981307444

Modifying MACE to accommodate genomic preselection effects

2019· article· en· W2981307444 on OpenAlexaff
P G Sullivan, Esa Mäntysaari, Gerben DeJong, Haïfa Benhajali

Bibliographic record

VenueJukuri (Luonnonvarakeskus Tietopalvelu) · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsCanadian Dairy Commission
Fundersnot available
KeywordsMaceSireGenomic informationBiologyComputer scienceComputational biologyGeneticsGenomeMedicineGeneAnimal scienceInternal medicine
DOInot available

Abstract

fetched live from OpenAlex

Sire evaluations from MACE are used as input for national genomic evaluations.The MACE results are based on traditional evaluation models ignoring genotypes, at both the national and international levels.The exclusion of genotypes is to avoid a cyclical and repeated double-counting of genomic information between national and international systems.Ignoring the genotypes, however, has the consequence of introducing bias in the MACE results, because the effects of genomic preselection are not included in the MACE estimated breeding values of genomically preselected sires.The bias problem is especially relevant for most recent AI bulls, the young sires of most interest in current breeding programs.Current and future methods are discussed, which could be used to reduce genomic preselection biases in MACE, while still generating suitable MACE proofs that can be used as input to national genomic evaluation systems without double-counting the genomic information.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.062
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.988
Threshold uncertainty score0.065

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.062
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0020.004
Open science0.0020.003
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0110.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.230
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSimulation or modeling
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2019
Admission routes1
Has abstractyes

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