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Application of PHASES and ELAPSS scores to ruptured cerebral aneurysms: how many would have been conservatively managed?

2021· article· en· W2988363803 on OpenAlexaff
Christopher Alan Hilditch, Waleed Brinjikji, Anderson Chun On Tsang, Patrick Nicholson, Alex Kostynskyy, Michael Tymianski, Timo Krings, Ivan Radovanovic, Vitor PEREIRA

Bibliographic record

VenueJournal of Neurosurgical Sciences · 2021
Typearticle
Languageen
FieldMedicine
TopicIntracranial Aneurysms: Treatment and Complications
Canadian institutionsUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsMedicineSubarachnoid hemorrhageAneurysmCohortAnterior communicating arteryPosterior communicating arteryBasilar arteryMiddle cerebral arteryRadiologySurgeryCardiologyInternal medicineIschemia

Abstract

fetched live from OpenAlex

BACKGROUND: We calculated the PHASES and ELAPSS scores for a large cohort of ruptured intracranial aneurysms (RIA) in order to determine whether these RIA would have been pre-emptively treated or closely followed-up should they have been detected prior to rupture. METHODS: We retrospectively reviewed a consecutive series of RIA over a 20-year period. The primary outcome of this study was the PHASES score of each ruptured aneurysm included. Secondary outcomes were ELAPSS score and other risk factors for aneurysmal subarachnoid hemorrhage including aneurysm location, aneurysm size, aneurysm morphology, smoking and hypertension history, personal and family history of subarachnoid hemorrhage. Multiplicity of cerebral aneurysms was recorded. Descriptive statistics are reported. RESULTS: 700 consecutive ruptured aneurysms were included. Mean age at rupture was 56 (+/-13.5) years. Mean aneurysm size was 5.9 (+/-2.5) mm. Most common locations of ruptured aneurysms were the anterior cerebral/communicating artery (39%), posterior communicating artery (21%), middle cerebral artery (16%) and basilar terminus (7%). Mean PHASES score was 5.3 (+/-2.5) and 17% of the RIA had a PHASES score of 3 or less. Mean ELAPSS score was 13.89 (+/-7.05) and over half of the RIA included had a low risk of future growth. CONCLUSIONS: A reasonable percentage of ruptured aneurysms have a low calculated PHASES score and these aneurysms may have been managed conservatively should they have presented incidentally prior to rupture. Most ruptured aneurysms also had a low ELAPSS score and were at low risk of future growth. The use PHASES score and ELAPSS score alone when making treatment decisions could result in many aneurysms being treated conservatively or undergoing remote surveillance despite rupture potential.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.013
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.300
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations39
Published2021
Admission routes1
Has abstractyes

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