Efficacy of tilmicosin and tildipirosin for on-arrival treatment of bovine respiratory disease in fall-placed feedlot calves in western Canada
Bibliographic record
Abstract
A trial was conducted in a commercial finishing feedlot in southern Alberta, Canada using fall-placed steer calves to evaluate the comparative efficacy of metaphylactic treatment with tilmicosin or tildipirosin for control of bovine respiratory disease (BRD). First-pull treatment rates for BRD were significantly lower (P<0.01) in calves administered tildipirosin than those administered tilmicosin on arrival. There were no significant differences in BRD relapse rates, overall mortality, or BRD and histophilosis mortality. While calves treated with tildipirosin on feedlot entry had higher average daily gain (P=0.006) and lower dry-matter conversion (P=0.007) at 56 days-on-feed than those treated with tilmicosin, these performance differences were no longer significant (P>0.05) at 146 days-on-feed. Using current drug prices and based on differences in initial BRD treatment rates, tilmicosin had a net economic advantage of $6.85 CAN/head to those treated with tildipirosin on arrival.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".