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Record W2992081730 · doi:10.1037/neu0000608

Longitudinal changes in response time mean and inconsistency exhibit predictive dissociations for risk of cognitive impairment.

2019· article· en· W2992081730 on OpenAlexfundno aff
Stuart MacDonald, Robert S. Stawski

Bibliographic record

VenueNeuropsychology · 2019
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsnot available
FundersNatural Sciences and Engineering Research Council of CanadaNational Institute on AgingNational Institutes of Health
KeywordsCognitionPsychologyNeuropsychologyLogistic regressionMultinomial logistic regressionCognitive declineCognitive impairmentAudiologyDevelopmental psychologyClinical psychologyDemographyInternal medicineMedicineDementiaPsychiatryStatisticsDisease

Abstract

fetched live from OpenAlex

OBJECTIVE: Although mean response time (RT) is a commonly used indicator of cognitive function, trial-to-trial variability (RT inconsistency [RTI]) represents a dissociable dimension of performance arguably more sensitive for characterizing cognitive status. The present study explores whether (a) RT mean or inconsistency reflects a more dispositional characteristic of an individual, particularly with increased cognitive impairment; (b) RT mean and inconsistency exhibit comparable patterns of change across a 4-year period; and (c) these rates of change differentially predict cognitive status. METHOD: A sample of 304 adults (64-92 years) at baseline completed a choice RT task weekly for 4-5 weeks, repeating this protocol and a basic neuropsychological assessment annually for 4 years. Three cognitive status subgroups were identified at baseline and Year 4: healthy controls (HCs), as well as cognitively impaired-not-demented (CIND) status based upon single (CIND-S) and multiple (CIND-M) domains. RESULTS: < .01) were linked to increased likelihood of CIND-M classification at Year 4, independent of age, education, chronic health conditions, and mean RT. CONCLUSIONS: RT mean and RTI confer distinct sources of information about cognitive function and status. Overall, RTI holds promise as an early indicator of normal and pathological cognitive aging. (PsycINFO Database Record (c) 2020 APA, all rights reserved).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.465

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.323
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations28
Published2019
Admission routes1
Has abstractyes

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