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Record W2993594890 · doi:10.1038/s41375-019-0666-7

An MDS-specific frailty index based on cumulative deficits adds independent prognostic information to clinical prognostic scoring

2019· article· en· W2993594890 on OpenAlexaff
Rebecca Starkman, Shabbir M.H. Alibhai, Richard A. Wells, Michelle Geddes, Nancy Zhu, Mary‐Margaret Keating, Brian Leber, Lisa Chodirker, Mitchell Sabloff, Grace Christou, Heather A. Leitch, Ève St‐Hilaire, Nicholas Finn, A. Shamy, Karen Yee, John M. Storring, Thomas J. Nevill, Robert Delage, Mohamed Elemary, Versha Banerji, Martha Lenis, Aksharh Kirubananthaan, Alexandre Mamedov, Liying Zhang, Kenneth Rockwood, Rena Buckstein

Bibliographic record

VenueLeukemia · 2019
Typearticle
Languageen
FieldMedicine
TopicFrailty in Older Adults
Canadian institutionsDalhousie UniversityUniversité LavalNova Scotia Health AuthorityRoyal Victoria HospitalRoyal Victoria Regional Health CentreVancouver General HospitalPrincess Margaret Cancer CentreDr. Georges-L.-Dumont University Hospital CentreSt. Paul's HospitalCentre hospitalier de l'Université LavalAlberta Hospital EdmontonUniversity of British ColumbiaMcGill University Health CentreUniversity of OttawaQueen Elizabeth II Health Sciences CentreCancerCare ManitobaUniversity of Alberta HospitalHealth Sciences CentreUniversity Health NetworkJuravinski Cancer CentreJewish General HospitalSunnybrook Health Science Centre
Fundersnot available
KeywordsMedicineMultivariate analysisInternal medicineMultivariate statisticsInternational Prognostic Scoring SystemQuality of life (healthcare)Prospective cohort studyConfidence intervalMyelodysplastic syndromesStatistics

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.049
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.330
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations34
Published2019
Admission routes1
Has abstractno

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