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Record W2994045108

The Friction Coefficient of Commercially Available Contact Lenses at a Cornea-Contact Lens Biointerface

2012· article· en· W2994045108 on OpenAlexaffvenue
Amanda Chan

Bibliographic record

VenueJournal of undergraduate research in Alberta · 2012
Typearticle
Languageen
FieldMedicine
TopicOcular Surface and Contact Lens
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsContact lensCorneaMaterials scienceLens (geology)WettingOphthalmologyCoefficient of frictionSilicone hydrogelBiomedical engineeringComposite materialAbrasion (mechanical)OpticsMedicine
DOInot available

Abstract

fetched live from OpenAlex

Background: At the ocular surface, epithelial cells are subject to shear and frictionforces during blinking. This can lead to wear damage, especially when there isinadequate lubrication in the presence of a compromised tear film1. Contact lenses areassociated with increased lid wiper damage, epitheliopathy and tear film instability2caused by increased friction due to the lens material3. This may lead to dry eye disease.Due to this, lenses often include agents that attempt to improve surface properties.These properties, particularly friction, are therefore paramount to preventing ocularsurface damage and discomfort.Methods: A custom cornea-contact lens biomechanical friction test was used totest commercially available contact lenses (Air Optix Aqua, Acuvue Oasys, Acuvue2,and Acuvue TruEye Dailies) The contact lenses and human corneas (obtained fromLions Eye Bank, n=5) were articulated against each other in a saline bath at effectivesliding velocities between 0.3-30 mm/sec and under loads of approximately 12-32 kPa.Friction coefficients were calculated from the axial load and torque measured duringarticulation of the test surfaces.Results: Kinetic friction coefficients, , in saline for each lens wasapproximately 0.080.02, 0.120.04, 0.150.05 and 0.090.02 for Acuvue2, Air Optix,TruEye and Oasys respectively (meansem). Values of in TruEye weresignificantly greater than those in both AC2 and Oasys (p 0.05).Conclusions: TruEye, a silicone hydrogel daily wear lens, had higher friction thanboth Oasys and Acuvue2, which were not significantly different from each other. Theseresults suggest that the unique wetting agent contained in Oasys and TruEye do notsignificantly affect in vitro friction measurements. Future experiments will examine ifadding ocular lubricants, such as hyaluronan and/or lubricin, can further reduce thefriction of these lenses and ultimately improve in vivo wear.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.079
GPT teacher head0.349
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2012
Admission routes2
Has abstractyes

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