Ependymoma arising from the third ventricle mimicking optic neuritis in a dog
Bibliographic record
Abstract
Neurological examination of a 4.5‐year‐old female neutered labrador retriever was consistent with a lesion in the subcortical visual pathway (mainly affecting the left retina or optic nerve, and less likely the optic chiasm or right optic tract). Ophthalmic examination was unremarkable. MRI revealed enlargement of the left optic nerve and optic chiasm. A presumptive diagnosis of immune‐mediated optic neuritis was made and immunosuppressive therapy was commenced. The dog re‐presented 14 days later due to progressive deterioration and generalised seizure activity, and was euthanased. Postmortem examination revealed an anaplastic ependymoma extending from the rostral thalamus along the left optic nerve. Ependymoma can therefore mimic an optic neuropathy, such as immune‐mediated optic neuritis, and should be considered as a differential diagnosis.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.004 | 0.002 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".