Bibliographic record
Abstract
Dermatitis herpetiformis (DH) is an inflammatory cutaneous disease with a chronic relapsing course, pruritic polymorphic lesions and typical histopathological and immunopathological findings. It is now considered the specific cutaneous manifestation of coeliac disease (CD). DH usually presents with symmetrical, grouped, erythematous papules, urticarial plaques, vesicles and secondary excoriations involving the extensor surfaces of the knees, elbows, shoulders, buttocks, sacral region, neck, face and scalp. Typical histopathological findings consist of fragile, subepidermal vesicles with accumulation of neutrophils at the papillary tips. Direct immunofluorescence is the gold standard for diagnosis and shows granular IgA deposition at the dermal papillae. Positive IgA antitissue transglutaminase (tTG), IgA antiendomysium antibodies (EMAs) and IgA antiepidermal transglutaminase (eTG) are considered specific and sensitive serological markers for DH. Both DH and CD occur in gluten-sensitive individuals, share the same HLA haplotypes (DQ2 and DQ8) and improve following administration of a gluten-free diet (GFD). Although life-long GFD is the treatment of choice for DH, it takes a long time for the cutaneous manifestations to resolve; thus, dapsone is highly recommended during the first 12–24 months of treatment. Patients with DH should be carefully monitored due to the association with intestinal malabsorption, autoimmune diseases and/or lymphoma.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.011 | 0.003 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".