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Record W2998511841 · doi:10.5772/intechopen.90177

Bioavailability and Effects of Polystyrene Nanoparticles in <i>Hydra circumcincta</i>

2019· book-chapter· en· W2998511841 on OpenAlex
J. L. Auclair, Brian Quinn, François Gagné

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueIntechOpen eBooks · 2019
Typebook-chapter
Languageen
FieldEnvironmental Science
TopicMicroplastics and Plastic Pollution
Canadian institutionsEnvironment and Climate Change Canada
FundersEnvironment and Climate Change Canada
KeywordsLernaean HydraBioavailabilityChemistryGlutathioneToxicityOxidative stressMicroplasticsBiophysicsEnvironmental chemistryBiochemistryBiologyCell biologyPharmacologyEnzyme

Abstract

fetched live from OpenAlex

The release of nanoplastics (NPs) from the weathering and degradation of plastics in the environment is an important concern to aquatic ecosystems. The purpose of this study was to examine the bioavailability and toxicity of 50 and 100 nm fluorescently labeled polystyrene nanoplastics (NP) to the invertebrate Hydra attenuata. The hydrae were exposed to increasing concentrations of 50 and 100 nm NPs (1.25-80 mg/L) for 96 h at 20°C. A subgroup of hydra was depurated in media to determine the persistence of effects. The results revealed that the animals accumulated detectable amounts fluorescent NP and produced morphological changes at a threshold concentration between 5 and 10 mg/L. The hydrae were able to eliminate 76 and 78% of the 50 and 100 nm NPs, respectively. A characteristic tentacle detachment from the body was observed. Biochemical markers were also determined in exposed organisms and increased glutathione S-transferase (GST) activity, oxidative damage and neutral lipids levels that persisted after the 24 h. In conclusion, NPs are bioavailable to Hydra, produce morphological changes and increase oxidative stress and neutral lipids. The formation of neutral lipids could be the result of reduced food assimilation or a means for the elimination of NPs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.661
Threshold uncertainty score0.859

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.180
Teacher spread0.175 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it