27th Annual Computational Neuroscience Meeting (CNS*2018): Part Two
Bibliographic record
Abstract
benefit from a separation of model parameters and implementation. To address these issues, we re-implemented the model using NetPyNE (www.netpy ne.org), a high-level Python interface to the NEURON simulator, which facilitates the development, parallel simulation and analysis of biological neuronal networks [6]. NetPyNE employs a standardized declarative format to describe the model specifications, and can then generate an efficiently parallelized NEU-RON model. It also provides a large number of analysis functions that enable further exploration of the model and allows exportation to NeuroML, a standard format for computational models. Our Net-PyNE implementation is able to reproduce the results of the original model, but using a clean and powerful declarative language, which makes this complex model accessible to a wider community of neuroscientists. Furthermore, we analyse and explore the model in new ways, including connectivity analysis, computation of LFP spectra and information flow. We also perform novel manipulations to elucidate the relation between neuronal and synaptic loss, involved in Alzheimer's disease, and memory recall performance.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.004 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.003 | 0.002 |
| Open science | 0.002 | 0.004 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.124 | 0.050 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".