Molecular Diagnosis of Babesia canis Infection with Concurrent of Evans Syndrome in a Labrador Dog
Bibliographic record
Abstract
Clinical case is five years old female Labrador dog presented to Small Animal Medicine unit of TVCC, VCRI, Orathanadu. History is dullness and anorexia two days. Recurrent tick infestations, anemic and thrombocytopenic crisis were regularly. Vaccination and deworming were regularly. Physical examination revealed dullness, pale mucosa, vital parameters were normal and ticks on interdigital space and in ears were noticed. Distended abdomen, hepatosplenomegaly and petechial hemorrhage on ventral abdomen were observed. Hematology revealed anemia and thrombocytopenia. Negative for blood born parasites in peripheral blood smear. Serum biochemical and urine analysis found to be normal. Serum and EDTA blood were submitted for molecular testing. Flow cytometry revealed Immune-mediated hemolytic anemia (IMHA) and Immune-mediated thrombocytopenia (IMTP). MAT negative for leptospira. Babesia canis positive by PCR method at 394bp. Haematology alteration was studied before and after therapy. Ultrasonography revealed hepatosplenomegaly. Based on PCR and flow cytometry the case was confirmed Evans syndrome with Concurrent Babesia canis in a Labrador dog. Dog treated with Inj. Diminazene aceturate @ 3.5mg/kg IM single dose, Inj. Ringers lactate @ 100 ml IV, Inj. Ascorbic acid @ 5 ml IV, Inj. Vitamin B complex @ 1ml IV, Inj. Prednisone @ 0.5mg/ kg IM, Tab. Doxycycline @ 10mg/kg PO and Syrup. Thrombup @ 15 ml BID PO. Dog showed clinical improvement as well as hematology parameters.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".