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A Healthcare Cost Calculator for Older Patients Over the First Year After Renal Transplantation

2019· article· en· W3006398448 on OpenAlexaffabout
Rui Fu, Nicholas Mitsakakis, Peter C. Coyte

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicRenal Transplantation Outcomes and Treatments
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsCalculatorTransplantationHealth careMedicineKidney transplantationRegressionEnd stage renal diseaseIntensive care medicineDiseaseEmergency medicineComputer scienceSurgeryInternal medicineStatisticsMathematics

Abstract

fetched live from OpenAlex

Forecasting tools that accurately predict post-transplantation healthcare use of older end-stage renal disease (ESRD) patients are needed at the time of transplantation in order to ensure smooth care delivery in the post-transplant period. We addressed this need by developing a machine-learning-based calculator that predicts the cost of healthcare for older recipients of a deceased-donor kidney over the first year following transplantation. Regression tree and regularized linear regression methods, including ridge regression, lasso regression and elastic net regression were explored on all cases of deceased-donor renal transplants performed for patients aged over 60 in Ontario, Canada between March 31, 2002 and April 31, 2013 (N=1328), The optimal model (lasso) identified age, membership of one of 14 regionalized Local Health Integration Networks, blood type, sensitization, having diabetes as the primary case of ESRD, total healthcare costs in the 12-month pre-workup period and the 6-month workup period to be inputs to the cost calculator. This cost calculator, in conjunction with clinical outcome information, will aid health system planning and performance to ensure better management of recipients of scarce kidneys.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.063
Threshold uncertainty score0.126

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.286
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes2
Has abstractyes

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