AB012. The effects of monocular deprivation do not accumulate across days in adults with normal vision
Bibliographic record
Abstract
Background: We investigate whether changes in visual plasticity induced by monocular deprivation can be maintained across multiple days. It has been known that monocular deprivation strengthens the deprived eye in adults with normal vision for a short period of time (30–60 minutes). This has been shown through a variety of visual tasks such as binocular combination and rivalry. Methods: Ten subjects were recruited and patched for five consecutive days for two hours. We used a binocular phase combination task to measure the subjects’ sensory eye balances. We initially measured their baseline of sensory eye balance, patched their dominant eye, and then conducted post-patching measurements at 0, 3, 6, 12, 24 and 48 minutes after patching. Results: We performed a 2-way ANOVA (Before vs. after patching × Day); we found that although the effect of monocular deprivation on the deprived eye was significant, F (1,9) = 17.32, P=0.002, the effect of Day was not. Conclusions: Hence we found no accumulation of the patching effect across five days in healthy adults. This suggests that the degree of remnant neural plasticity in adult primary visual cortex may be too limited to be exploited therapeutically.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".