Brinster Spermatogonial Stem Cell Transplantation 25th Anniversary Symposium
Bibliographic record
Abstract
ABSTRACT The Symposium, co-sponsored by the Institute of Regenerative Medicine, the University Research Foundation, the Center for Research on Reproduction and Women’s Health, the Penn Center for the Study of Epigenetics in Reproduction, and Penn Vet at the University of Pennsylvania, commemorated the 25 th anniversary of the first publications describing spermatogonial stem cell (SSC) transplantation in mice. This transformative approach has propelled advances in our understanding of germ cell biology, has been translated to a variety of vertebrate species, and holds translational potential for fertility restoration in patients. The symposium opened with a lecture by Dr. Brinster reflecting on the origin of the work, as well as advances over the 25 years up to present ongoing studies. Following Dr. Brinster’s remarks, 10 lectures were presented by distinguished scientists, including several of Dr. Brinster’s former trainees and colleagues. The symposium closed with a keynote lecture by Dr. David Page. Topics ranged from aspects of basic SSC biology to applications in large animal models and potential translation to treating human male infertility. Many of the studies presented directly resulted from SSC transplantation technology highlighting its tremendous impact in advancing the field. The Symposium program and the lectures can be found at https://spark.adobe.com/page/jS0cDLzLHvOiJ
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".