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Heart Rate Variability during Heat Exposure is not Affected by Short‐term Passive Heat Acclimation in Young Healthy Participants

2020· article· en· W3017334584 on OpenAlexaffabout
Philippe Gendron, Hugo Gravel, Hadiatou Barry, Daniel Gagnon

Bibliographic record

VenueThe FASEB Journal · 2020
Typearticle
Languageen
FieldMedicine
TopicThermoregulation and physiological responses
Canadian institutionsUniversité de MontréalUniversité du Québec à Trois-RivièresMontreal Heart Institute
Fundersnot available
KeywordsAcclimatizationHeart rateHeart rate variabilityHyperthermiaBradycardiaCardiologyMedicineAnimal scienceStroke volumeInternal medicineChemistryBlood pressureBiology

Abstract

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INTRODUCTION Heat acclimation attenuates the increase in heart rate during heat exposure. This heat acclimation‐induced bradycardia has been associated with increased stroke volume due to blood volume expansion. However, exercise‐induced heat acclimation also modulates cardiac parasympathetic activity, as measured through heart rate variability (HRV). Therefore, it is possible that modulation of cardiac autonomic activity could contribute to the effect of heat acclimation on heart rate during heat exposure. The purpose of this study was to determine if HRV during heat exposure is modified by short‐term passive heat acclimation. METHODS Fifteen healthy adults (27 ± 5 years, 5 females/10 males) underwent heat exposure in a water‐perfused suit to increase esophageal temperature (Tes) by 1.2°C, before and after a 7‐day controlled hyperthermia protocol. During heat exposure, R‐R interval was measured continuously with a 5‐lead electrocardiogram and used to calculate heart rate (HR), mean normal‐to‐normal intervals (NN), standard deviation of NN intervals (SDNN), root mean square of successive NN interval differences (RMSSD), low‐frequency (LF) and high‐frequency spectral power (HF) and the LF‐to‐HF power ratio (LF/HF). The acclimation protocol consisted of hot water immersion to elevate and subsequently maintain rectal temperature ≥38.6°C for 60 minutes once a day for 7 consecutive days. Variables were compared between the pre and post acclimation visit at baseline and at increases in Tes of 0.6°C and 1.2°C. RESULTS Heat acclimation lowered resting Tes (36.81 ± 0.29 to 36.53 ± 0.32°C, P <0.001) and, consequently absolute Tes during heat exposure. When analyzed as a function of the change in Tes from baseline, no difference was observed for HR ( P =0.072) at baseline (59 ± 10 vs. 57 ± 9 bpm), +0.6°C (88 ± 12 vs. 86 ± 11 bpm), and +1.2°C (103 ± 13 to 99 ± 12 bpm). Similarly, NN (baseline: 1049 ± 172 vs. 1081 ± 162 ms, +0.6°C: 691 ± 104 vs. 705 ± 100 ms, +1.2°C: 595 ± 74 vs. 600 ± 96 ms, P =0.295), SDNN (baseline: 84 ± 38 vs. 90 ± 37 ms, +0.6°C: 43 ± 15 vs. 45 ± 15 ms, +1.2°C: 28 ± 9 vs. 31 ± 8 ms, P =0.294) and RMSSD (baseline: 83 ± 49 vs. 93 ± 57 ms, +0.6°C: 19 ± 9 vs. 19 ± 14 ms, +1.2°C: 9 ± 4 vs. 9 ± 3 ms, P =0.336) did not differ after heat acclimation. No effect of heat acclimation was also observed for LF ( P =0.339), HF ( P =0.509) and LF/HF ratio ( P =0.449). CONCLUSIONS These results suggest that short‐term, passive and isothermic heat acclimation does not modulate cardiac autonomic activity during passive heat exposure in healthy young adults. Support or Funding Information Natural Sciences and Engineering Research Council of Canada, Canada Foundation for Innovation and Montreal Heart Institute Foundation.

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How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.319
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2020
Admission routes2
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