Watch out for slowly progressive weakness of the distal upper limb: it could be chronic acquired demyelinating neuropathy!
Bibliographic record
Abstract
In clinical practice, physicians occasionally encounter patients with complaints of progressive weakness of the hand or wrist. Distal upper limb weakness is commonly caused by compressive neuropathy of the spinal cord (i.e., cervical spondylotic myelopathy), spinal nerve roots (i.e., foraminal stenosis), or peripheral nerves (i.e., tardy ulnar neuropathy, carpal tunnel syndrome, thoracic outlet syndrome, or anterior/posterior interosseous syndromes). However, forms of chronic acquired demyelinating neuropathy, such as multifocal motor neuropathy (MMN) and multifocal acquired demyelinating sensory and motor neuropathy (MADSAM), are occasionally the cause of distal upper limb weakness. However, many clinicians lack sufficient knowledge about the diagnosis of MMN and MADSAM. Consequently, patients with motor weakness caused by these disorders are frequently misdiagnosed and go without treatment for extended periods of time.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".