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“Visceral sensitivity index” in patients with IBS of diff erent ages

2020· article· en· W3023595483 on OpenAlexaboutno aff
Marina G. Mnatsakanyan, А. П. Погромов, O. V. Taschyan, K. Yu. Kolosova

Bibliographic record

VenueExperimental and Clinical Gastroenterology · 2020
Typearticle
Languageen
FieldMedicine
TopicGastrointestinal motility and disorders
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineIrritable bowel syndromeSomatizationAnxietyAlexithymiaDepression (economics)Internal medicineAnxiety scoreBiopsychosocial modelBeck Anxiety InventoryBeck Depression InventoryGastroenterologyPsychiatry

Abstract

fetched live from OpenAlex

The Irritable Bowel Syndrom (IBS) is one of the most widespread functional disorders of digestive tract (FD GIT). According to biopsychosocial model the anxiety concerning feelings from digestive tract plays a key role in maintenance and, perhaps, in development of IBS. J. Labus proposed the new questionnaire — VSI — the Visceral Sensitivity Index or the index of gastrointestinal symptom-specifi c anxiety, later validated only for patients with IBS. Aim: to estimate the value of VSI in patients with IBS depending on a sex, age and clinical subtype of IBS and its correlation with a depression, anxiety and alexihymia. Methods: 245 patients with IBS were examined (women — 183, men — 62), middle age 45.31 ± 6.9 years (19–81). Initially, 10 patients from 245 selected patients with IBS did not answer to the questionnaire. 7 patients did not fill out the questionnaire. So, data from 228 patients with IBS which completely fill out the questionnaire was analyzed. According to the research objective the initial group of patients with IBS was divided into two subgroups: up to 45 years (the 1st group) and 45 years and older (the 2nd group). The 1st group included 120 patients; the 2nd group — 108 patients. IBS was confirmed by the diagnostic criteria of IBS according to Rome III (2006). Depression was assessed by the Beck’s Depression Inventori (BDI), anxiety — by the Stait-Trait Anxiety Inventory (STAI) (by Spielberger-Hanin), alexithymia — by the Toronto Alexithymia Scale (TAS). Results: The VSI was higher in the senior age group of IBS patients (2nd group), at the same time there were no gender differences in both groups. The greatest values of VSI were observed at patients with IBS-D subtype in both age groups. VSI was an independent indicator in the 1st subgroup of patients with IBS (age up to 45 years) while in the 2nd subgroup (senior age group) weak correlation with a depression and personal anxiety (r ≥0.4) was observed. Conclusion: The VSI can be used as the independent test refl ecting a psychoemotional condition of patients with IBS at a diagnostic stage.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.391

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.289
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations2
Published2020
Admission routes1
Has abstractyes

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