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Record W3024784069 · doi:10.1149/ma2020-01432497mtgabs

Phenolic Antioxidants: Redox Properties and Antioxidant Activities

2020· article· en· W3024784069 on OpenAlexaff
Sanela Martić

Bibliographic record

VenueECS Meeting Abstracts · 2020
Typearticle
Languageen
FieldChemistry
TopicFree Radicals and Antioxidants
Canadian institutionsTrent University
Fundersnot available
KeywordsChemistryRedoxAntioxidantHydroxyl radicalPhenolsCyclic voltammetryReactive oxygen speciesReactivity (psychology)Pro-oxidantPolyphenolOrganic chemistryRadicalCombinatorial chemistryElectrochemistryBiochemistry

Abstract

fetched live from OpenAlex

Phenolic compounds are known for their antioxidant properties, which is important in the biological setting [1]. The cellular damage induced by reactive oxygen species, ROS, or others leads to diseases. However, foods or drugs which contain phenolic moieties are viable antioxidants which reduce ROS and minimize cell damage. Hence, greater understanding of this class of compounds will lead to an ideal antioxidant with tailored properties for applications in biology, food safety, among others. The relationship between structure-properties-function was evaluated by using voltammetric methods. We have explored redox properties of phenol-based compounds, such as tert-butylhydroxyphenol and its analogues by using Cyclic Voltammetry (CV) as well as Square-Wave Voltammetry (SWV) in order to rank order such compounds based on their redox potentials and structural parameters [2]. We have discovered that under electrochemical conditions, rather than chemical ones, such compounds may undergo cross-coupling reactions leading to photochromic products. The reactivity of such phenolic analogues was also explored by CV in the study with reactive oxygen species, specifically, superoxide anion radical [3]. More recently, we have started exploring compounds with multiple hydroxyl groups, such as flavonoids. The research findings on a variety of hydroxyl-containing aromatics will be presented and described. 1. Ingold, K. U., Pratt, D. A. Advances in radical-trapping antioxidant chemistry in the 21st century: a kinetic and mechanisms perspective. Chem. Rev. 2014, 9022-9046. 2. Zabik, N., Virca, C. N., McCormick, T., Martic-Milne, S. Selective electrochemical versus chemical oxidation of bulky phenols. J. Phys. Chem. B, 2016, 120, 8914–8924. 3. Zabik, N., Anwar, S., Ziu, I., Martic-Milne, S., Electrochemical reactivity of bulky-phenols with superoxide anion radical. Electrochim. Acta, 2019, 296, 174-180

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.224
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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