MétaCan
Menu
Back to cohort
Record W3028416865 · doi:10.1074/jbc.ra120.013277

The magnesium transporter NIPAL1 is a pancreatic islet–expressed protein that conditionally impacts insulin secretion

2020· article· en· W3028416865 on OpenAlexafffund
Yousef Manialawy, Saifur R. Khan, Alpana Bhattacharjee, Michael B. Wheeler

Bibliographic record

VenueJournal of Biological Chemistry · 2020
Typearticle
Languageen
FieldNursing
TopicMagnesium in Health and Disease
Canadian institutionsUniversity Health NetworkToronto General HospitalSt. Michael's HospitalUniversity of Toronto
FundersBanting and Best Diabetes Centre, University of TorontoCanadian Institutes of Health ResearchGovernment of CanadaDiabetes Canada
KeywordsIsletEndocrinologyInternal medicineTransporterPancreatic isletsSecretionInsulinMagnesiumChemistryBiologyMedicineGeneBiochemistry

Abstract

fetched live from OpenAlex

expression is regulated by extracellular magnesium and that down-regulation of this transporter decreases glucose-stimulated insulin secretion and intracellular insulin content, particularly under conditions of hypomagnesemia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.068
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.264
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations21
Published2020
Admission routes2
Has abstractyes

Explore more

Same venueJournal of Biological ChemistrySame topicMagnesium in Health and DiseaseFrench-language works237,207