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Record W3028541 · doi:10.1007/bf01606559

The large radius human centrifuge 'A human hypergravity habitat, H 3

2009· article· en· W3028541 on OpenAlexaff
Jack J. W. A. van Loon, Floris L. Wuyts, N. Bäcker, Johan Berte, Kim Yoon Bok, J.E. Bos, Eric L. Groen, R. Boyle, N. Bravenoer, M. Eekhoff, Alexander Choukèr, Gilles Clément, Patrick Cras, Pierre Denise, Dieter Felsenberg, K. Fong, Charles A. Fuller, Martina Heer, Helmut Hinghofer‐Szalkay, Satoshi Iwase, John M. Karemaker, Dag Linnarsson, Christian Lüthen, Edwin Mulder, M. Narici, Peter Norsk, William H. Paloski, M. Rutten, Raoul Saggini, André Stephan, Oliver Ullrich, L. Vautmans, Laurence R. Young

Bibliographic record

VenueBulletin of Environmental Contamination and Toxicology · 2009
Typearticle
Languageen
FieldMedicine
TopicSpaceflight effects on biology
Canadian institutionsCanadian Nautical Research Society
Fundersnot available
KeywordsHypergravityWeightlessnessCentrifugeSpaceflightGravity of EarthBed restGravitationAstrobiologyPhysicsAerospace engineeringEngineeringMedicineGravitational fieldSurgeryClassical mechanics

Abstract

fetched live from OpenAlex

Over the last decades a significant body of knowledge has been gained on the adaptation of the human body going into near weightlessness conditions as well as for the re-adaptation to 1xg Earth conditions after an orbital space flight. Ground-based paradigms for microgravity simulation have been developed such as head down tilted bed rest or dry-immersion studies. In such systems adaptations of the human body to long term immobilization and increased upper-body fluid shifts bed have been studied. But could we learn something on human body adaptations to altered gravity conditions using centrifuges? How does the body adapt to a long duration (days, weeks or longer) exposure to a hypergravity environment? And, once the body has fully adapted to a hypergravity environment, how does it re-adapt going from a hypergravity condition to a relatively hypo-gravity condition of 1xg, or even going from centrifuge / hypergravity environment into a bed-rest setting? Can such transitions learn us something about the gravity transitions as a crew will experience going to Moon or Mars. Is hypergravity therefore a good model to study the effect of re-entry in gravitational environments after long duration space flight? We established a Topical Team sponsored by ESA ans supported by NASA and JAXA in which we address the issues as mentioned above. We like to address the questions for all organ systems known to change under altered gravity conditions. We will identify to which gravity levels the human body can be exposed to for longer periods of time and what protocols could be applied to address the questions at hand. We also need to identify if and how we could perform such long duration hypergravity and re-adaptation studies. Issues like ethics, safety and required technology are addressed. The final outcome of the ESA Topical Team will be a clear answer about the feasibility of long duration hypergravity, and if and how hypergravity studies can provide useful knowledge to support future space flight on the one hand and the medical issues in e.g. the ageing population with its contemporary lifestyle on the other hand (osteoporosis, cardiovascular diseases, obesity).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.249
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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