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Identification of carotid plaque microcalcification by Micropure imaging

2017· article· en· W3028878021 on OpenAlexaboutno aff
Ying He, Dan Ye, Fei Hua, Xuegan Lian, Jian Wu, Ying Jiang, Chunxian Yue, Song Yang, Ning Wei, Meng Liu

Bibliographic record

VenueChinese Journal of Neuromedicine · 2017
Typearticle
Languageen
FieldMedicine
TopicCerebrovascular and Carotid Artery Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsMicrocalcificationMedicineStroke (engine)RadiologyReceiver operating characteristicCarotid arteriesIschemic strokeCardiologyInternal medicineIschemiaMammography

Abstract

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Objective To explore the relationship between carotid plaque microcalcifcation and ischemic stroke (including transient ischemic attack) and the value of carotid microcalcification in predicting ischemic stroke. Methods Twenty-six patients in accordance with atherothrombosis models classified by Korean modified TOAST classification were enrolled in this study from November 2016 to March 2017. The microcalcification of the bilateral carotid was detected by Micropure imaging and the severity of intracranial ischemic focal lesions was evaluated by Alberta stroke programme early CT scale (ASPECT). The relation of ASPECT scores with microcalcification of the bilateral carotid was analyzed, and the value of carotid microcalcification in predicting ischemic stroke was analyzed by receiver operating characteristic curve method. Results Microcalcifition was detected in 27 of the total 52 carotids (51.92%) in 19 patients, which localized in the fibrous cap in 23 carotids (85.19%) and the basilar part of the plaque in 4 carotids (14.81%). The microcalcification surrounded the macrocalcifiation in 14 carotids (51.85%). The ASPECT scores were 10.85±1.43 in the microcalcifition side, which were significantly higher than those in the side without microcalcifition (11.80±1.19, t=2.584, P=0.013). The area under the curve was 0.673, with sensitivity of 0.667 and specificity of 0.680. Conclusion Micropure imaging maybe a new approach to detect the carotid microcalcification, and plaques with microcalcifition may easily cause ipsilateral ischemic stroke. Key words: Carotid; Microcalcification; Ultrsound; Stroke; Micropure imaging

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.619
Threshold uncertainty score0.432

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.276
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2017
Admission routes1
Has abstractyes

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