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Record W3029070434 · doi:10.1101/2020.05.28.20115782

Monitoring sick leave data for early detection of influenza outbreaks

2020· preprint· en· W3029070434 on OpenAlexfundno aff
Tom Duchemin, Jonathan Bastard, Pearl Anne Ante-Testard, Rania Assab, Oumou Salama Daouda, Audrey Duval, Jérôme‐Philippe Garsi, Radowan Lounissi, Narimane Nekkab, Helene Neynaud, David R. Smith, William Dab, Kévin Jean, Laura Temime, Mounia N. Hocine

Bibliographic record

VenuemedRxiv · 2020
Typepreprint
Languageen
FieldMedicine
TopicData-Driven Disease Surveillance
Canadian institutionsnot available
FundersCanadian Institutes of Health ResearchAssociation Nationale de la Recherche et de la TechnologieAgence Nationale de la RechercheInstitut National de la Santé et de la Recherche MédicaleStyrelsen för Internationellt Utvecklingssamarbete
KeywordsOutbreakSick leaveAbsenteeismMedicineEmergency medicineEnvironmental healthVirologyPhysical therapy

Abstract

fetched live from OpenAlex

Background - Workplace absenteeism increases significantly during influenza epidemics. Sick leave records may facilitate more timely detection of influenza outbreaks, as trends in increased sick leave may precede alerts issued by sentinel surveillance systems by days or weeks. Sick leave data have not been comprehensively evaluated in comparison to traditional surveillance methods. Aim - To study the performance and the feasibility of using a detection system based on sick leave data to detect influenza outbreaks Methods - Sick leave records were extracted from private French health insurance data, covering on average 209,932 companies per year across a wide range of sizes and sectors. We used linear regression to estimate the weekly number of new sick leave spells from 2010 to 2017 in 12 French regions, adjusting for trend, seasonality and worker leaves. Outbreaks were detected using a 95%-prediction interval. This method was compared to results from the French Sentinelles network, a gold-standard primary care surveillance system currently in place. Results - Using sick leave data, we detected 92% of reported influenza outbreaks between 2016 and 2017, on average 5.88 weeks prior to outbreak peaks. Compared to the existing Sentinelles model, our method had high sensitivity (89%) and specificity (86%), and detected outbreaks on average 2.5 weeks earlier. Conclusion - Sick leave surveillance could be a sensitive, specific and timely tool for detection of influenza outbreaks.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.045
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.115
GPT teacher head0.359
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2020
Admission routes1
Has abstractyes

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