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Diagnostic significance of the difference values between Mini-Mental State Examination and Montreal Cognitive Assessment in elderly patients with dementia

2015· article· en· W3029552606 on OpenAlexaboutno aff
Xiao Zhang, Xinrui Yuan, Rui Zhu, Yiyao Cui

Bibliographic record

VenueZhonghua laonian yixue zazhi · 2015
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsnot available
Fundersnot available
KeywordsDementiaMontreal Cognitive AssessmentReceiver operating characteristicDementia with Lewy bodiesMini–Mental State ExaminationVascular dementiaFrontotemporal dementiaAudiologyClinical Dementia RatingCognitive impairmentMedicineDifferential diagnosisLewy bodyCognitionPsychiatryPsychologyInternal medicineDiseasePathology

Abstract

fetched live from OpenAlex

Objective To investigate the diagnostic significance of the difference values between Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA)in elderly patients with dementia. Methods 331 elderly patients with dementia were collected from out-patients in our hospital. There were 148 people with Alzheimer′s disease (AD), 87 cases with vascular dementia (VaD), 44 cases with mixed dementia (MD), 41 cases with frontotemporal dementia (FTD) and 11 cases with dementia with Lewy bodies (DLB). MMSE and MoCA were applied to test the cognitive impairment separately. Results The difference values between MMSE and MoCA was (3.3±1.7) points, (6.6±2.1) points, (6.6±2.1) points, (5.4±2.3) points, (6.1±1.9) points in AD, VaD, MD, FTD and DLB group respectively, and there were statistical differences among the five groups (F=46.420, P=0.000). Statistical differences were found in the difference values between MMSE and MoCA between dementia patients with AD and non-AD (t=-13.429, P=0.000). According to receiver operating characteristic curve (ROC curve), the optimal cut off point of the difference values between MMSE and MoCA for differential diagnosis between AD and non-AD dementia was 5 points, with 79.8% sensitivity and 78.4% specificity, and area under the curve was 0.848 (95%CI: 0.807-0.890). Conclusions The difference values between MMSE and MoCA may be one of parameters for differential diagnosis between AD and non-AD dementia. Key words: Dementia; Psychiatric status rating scales; Cognition

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.062
Threshold uncertainty score0.545

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.286
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2015
Admission routes1
Has abstractyes

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