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Gait disorders research in Alzheimer's disease

2016· article· en· W3029559987 on OpenAlexaboutno aff
Yun Hua, Xiaoxia Chen, Jie Cheng

Bibliographic record

VenueZhongguo zonghe linchuang · 2016
Typearticle
Languageen
FieldMedicine
TopicTraditional Chinese Medicine Studies
Canadian institutionsnot available
Fundersnot available
KeywordsMontreal Cognitive AssessmentBerg Balance ScaleGaitBalance (ability)Cognitive impairmentCognitionPsychologyMemory spanPhysical medicine and rehabilitationPhysical therapyTimed Up and Go testMedicineMini–Mental State ExaminationTrail Making TestInternal medicinePsychiatryWorking memory

Abstract

fetched live from OpenAlex

Objective To investigate the gait differences among patients with Alzheimer's disease(AD) and mild cognitive impairment(AD-MCI) and the person with normal cognitive function, and analyze the reasons for the abnormal gait. Methods Eighty patients were included and divided into 3 groups according to the cognitive status: noncognitive impairment(NCI group, n=30), patients with mild cognitive impairment(AD-MCI group, n=29), Alzheimer's disease(AD group, n=21). The mini-mental state examination(MMSE), the Montreal Cognitive Assessment(MoCA), Addenbrooke's Cognitive Examination(ACE-R), the connection test(TMT-A), Digit Span Test(DST), activities of daily living questionnaire(ADL) and associated gait and balance scale(5 times sit to stand test(FTSTT), 3 m walking test (TUG), Berg balance scale) were used to evaluate all research objects in each group. Results There were significant differences in NCI group compared with AD-MCI group and AD group in terms of FTSTT, TUG, Berg balance Scale and leg speed((9.59±2.39) s vs.(13.71±4.65) s vs.(14.15±4.20) s, (7.70±1.58) s vs.(11.13±3.02) s vs.(11.35±4.43) s, (54.20±1.56) points vs.(48.17±4.93) points vs.(48.10±5.46) points, (82.12±22.79) cm/s vs.(57.49±14.89) cm/s vs.(57.70±14.68) cm/s; P<0.05). There were significant differences in NCI group compared with AD-MCI group and AD group in terms of MMSE, MoCA, ACE-R, TMT-A, DST((28.67±1.27) points vs.(26.76±2.59) points vs.(21.86±5.29) points, (26.03±2.58) points vs.(22.39±5.05) points vs.(16.90±5.05) points, (85.80±5.90) points vs.(78.03±7.58) points vs.(60.95±13.99) points, (12.66±5.36) s vs.(18.99±11.46) s vs.(30.49±26.98)s, (18.60±4.64) points vs.(15.94±4.76) points vs.(12.86±5.23) points; P<0.05). Conclusion Gait disorder might be an early sign for cognitive impairment. Key words: Alzheimer's disease; Cognitive dysfunction; Gait disturbance

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.121
Threshold uncertainty score0.626

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.091
GPT teacher head0.377
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2016
Admission routes1
Has abstractyes

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