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Clinical effect of oral Xingshi decoction combined with warming needle moxibustion in treating acute knee osteoarthritis

2019· article· en· W3029753444 on OpenAlexaboutno aff
Ting Xu, Tingting Gu, Ting Li, Mingfeng Lu

Bibliographic record

VenueTraditional Chinese Medicine · 2019
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacological Effects of Natural Compounds
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineDecoctionErythrocyte sedimentation rateOsteoarthritisMoxibustionInternal medicineRheumatoid arthritisDiclofenac SodiumMethotrexateGastroenterologySurgeryAcupuncturePharmacologyPathology

Abstract

fetched live from OpenAlex

Objective To evaluate the effect of Xingshi decoction combined with warming needle moxibustion combined with conventional western medicine on acute knee arthritis. Methods A total of 86 patients with acute knee arthritis were randomly divided into two groups, 43 in each group. The control group took diclofenac capsules orally and methotrexate once a week, while the observation group took Xingshi decoction and warming needle moxibustion on the basis of the control group. Both groups were treated for 2 weeks. The Rheumatoid factor (RF), high sensitive C reactive protein (hs-CRP) and IL-1β were detected by ELISA, and pain rating index (PRI), VAS and present pain intensity (PPI) were evaluated by McGill pain questionnaire (SF-MPQ). The knee function was assessed by the evaluation scale, and the curative effect was evaluated by 28 joint disease activity-erythrocyte sedimentation rate (ESR) scores. Results The total effective rate was 88.4% (38/43) in the observation group and 62.8% (27/43) in the control group. There was significant difference between the two groups (Z=2.678, P=0.007). After treatment, ESR (30.95 ± 3.14 mm/h vs. 55.13 ± 3.28 mm/h, t=34.919), RF (81.36 ± 5.13 U/ml vs. 121.73 ± 7.25 U/ml, t=29.807), hs-CRP (10.13 ± 3.12 mg/L vs. 34.26 ± 3.17 mg/L, t=35.575), IL-1β (58.13 ± 3.12 pg/ml vs. 96.76 ± 3.17 pg/ml, t=56.952) of the observation group were significantly lower than those of control group (P<0.01); and PRI, VAS and PPI scores of SF-MPQ in observation group were significantly lower than those of control group (t values were 19.661, 11.056 and 23.524, respectively, P<0.01) and the scores of walking, swelling, sense of stability, strangulation and stair-climbing were significantly higher than those of the control group (t values were 11.071, 13.464, 9.102, 9.804, 10.012, respectively, P<0.01). Conclusions The Xingshi decoction combined with warming needle moxibustion is effective in treating acute knee arthritis. It can effectively relieve pain and inflammation of patients, thus improving knee joint function. It has certain clinical application value. Key words: Arthritis; Acute pain;  Xingshi decoction; Acupuncture points; Needle warming therapy; Moisten compress therapy; Comparative effectiveness research

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.434
Teacher spread0.365 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2019
Admission routes1
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