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Naoxintong capsules in treating vascular cognitive impairment

2012· article· en· W3029761607 on OpenAlexaboutno aff
Xinzhou Jia, Yaping Cui, Guiqing Wang

Bibliographic record

VenueCentral Plains Medical Journal · 2012
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disease Mechanisms and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineMontreal Cognitive AssessmentInternal medicineCognitive impairmentPillGastroenterologySignificant differenceMini–Mental State ExaminationMental stateTreatment and control groupsPsychiatryDisease

Abstract

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Objective To investigate the clinical effect of Naoxintong capsules in treating patients with vascular cognitive impairment(VCI).Methods Sixty patients with VCI were randomly divided into treatment group(30 cases)and control group(30 cases).The treatment group were treated with Naoxintong capsules(3 capsules,tid,for 3 months).The control group were treated with Nimotop tablets (1 pills,tid,for 3 months).Mini-Mental State Examination(MMSE),Montreal Cognitive Assessment (MoCA)were used for screening patients with VCI.All selected patients were followed up the MMSE,MoCA scores and the measured value of TG,TC,HDL-C,LDL-C and hs-CRP before treatment and 1 month later,2 months later,and 3 months after treatment.Their peripheral blood specimen were collected in the above-mentioned four time points.Results MMSE and MoCA scores were improved in both groups after treatment.There were significant differences before and after treatment in the two groups (P<0.05).The time when MMSE and MoCA scores changed significantly was a little bit later in the treatment group than that in the control group,but there were no significant difference between the two groups after three months of treatment(P>0.05).There were significant differences in the levels of TG,TC,HDL-C,LDL-C and hs-CRP before and after treatment in the treatment group(P<0.05).But there were no significant differences in the levels of the above-mentioned serum lipid and hs-CRP in the control group before and after treatment(P>0.05).Conclusions Naoxintong capsules have a certain effect in treating patients with vascular cognitive impairment.Its effect on improving the cognitive function is equal to Nimotop,and has effect of regulating blood tipids and reducing hs-CRP level,which Nimotop doesn't have. Key words: Naoxintong capsules; Nimotop; Vascular cognitive impairment; Cognitive function

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.431
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.278
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2012
Admission routes1
Has abstractyes

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