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Correlation between grading of MRI-determined thickness of knee synovitis and knee joint function and pain scores in end-stage osteoarthritis

2019· article· en· W3031602862 on OpenAlexaboutno aff
Ningjie Chen, Hui Zhao, Fengyun Hao, Hao Liu

Bibliographic record

VenueChin J Joint Surg(Electronic Edition) · 2019
Typearticle
Languageen
FieldMedicine
TopicMusculoskeletal synovial abnormalities and treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineOsteoarthritisWOMACSynovitisKnee JointRank correlationStage (stratigraphy)CorrelationPhysical therapyRadiologyNuclear medicineSurgeryInternal medicineArthritisPathology

Abstract

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Objective To investigate if MRI findings of the thickness of synovitis could be used as criteria for the indications of knee replacement. Methods Thirty-one patients with end-stage knee osteoarthritis (OA) were selected and received the following examinations: (1) noninvasive MRI evaluation for grading the synovial thickness of the investigated sites (i.e., medial and lateral parapatellar recesses, and medial and lateral suprapatellar pouches; synovitis was categorized into grade zero to three on the basis of the thickness); (2) determination of knee-joint pain scores (visual analogue scale, VAS score) and functional scores Western Ontario and McMaster Univerisities Osteoarthrifis index, WOMAC) before total knee arthroplasty (TKA). Pearson’s linear test or Spearman rank test was used to analyze the correlation between synovial thickness and WOMAC OA index, and VAS score. Results Statistical analysis revealed no significant differences in MRI synovial thickening grade across the different regions of the knee.No correlation existed between the grades of MRI-determined thickness for synovitis and knee joint function scores with pain score (rs=0.17, P>0.05; rs=0.32, P >0.05), as well as no correlation existed between the different regions of the knee and the above factors respectively. Conclusion The grade of MRI-determined thickness of synovitis shows no correlation with the subjective scores in the patients with end-stage knee OA, thus the grades of MRI-determined thickness cannot be used as criteria for knee joint replacement indications, and further study on the relation among MRI, VAS and WOMAC scores is still warranted. Key words: Osteoarthritis; Magnetic resonance imaging; Synovial membrane; Visual analog scale

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.060
Threshold uncertainty score0.921

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.218
Teacher spread0.208 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2019
Admission routes1
Has abstractyes

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