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Comparative study of direct mechanical thrombectomy and bridging therapy for acute anterior circulation large-artery occlusive stroke

2020· article· en· W3032103302 on OpenAlexaboutno aff
Haibing Ren, Huiqin Liu, Sisi Wang, Jianying Zhang, Wenjin Yang, Xiaohui Zhao, Ke Qing, Guodong Xiao, Yongjun Cao

Bibliographic record

VenueChinese Journal of Neuromedicine · 2020
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disease Mechanisms and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineThrombolysisModified Rankin ScaleStroke (engine)Bridging (networking)Glasgow Coma ScaleAnterior cerebral arterySurgeryCerebral infarctionArteryInternal medicineCardiologyMiddle cerebral arteryIschemic strokeMyocardial infarctionIschemia

Abstract

fetched live from OpenAlex

Objective To comparatively analyze the safety and efficacy of direct mechanical thrombectomy and bridging therapy for patients with acute anterior circulation large-artery occlusive stroke. Methods A total of 116 patients with acute anterior circulation large-artery occlusive stroke, admitted to our hospitals from October 2015 to March 2018, were chosen in our study; their clinical data were analyzed retrospectively. Among them, 63 patients accepted direct mechanical thrombectomy and 53 accepted bridging therapy. The preoperative baseline data and the diagnoses and treatments of the two groups were analyzed; the degrees of modified thrombolysis in cerebral infarction (mTICI), incidences of hemorrhage transformation and symptomatic intracranial hemorrhage, and modified Rankin scale (mRS) scores and mortality rate 90 d after operation were compared between the two groups. Results The preoperative Alberta stroke program early CT scale (ASPECTS) and Glasgow Coma Scale (GCS) scores of the direct mechanical thrombectomy group were significantly lower than those of the bridge therapy group (P 0.05). Conclusion The clinical efficacy and safety of direct mechanical thrombectomy and bridging therapy for patients with acute anterior circulation large-artery occlusive stroke are similar. Key words: Ischemic stroke; Anterior circulation; Mechanical thrombectomy; Intravenous thrombolysis; Bridging therapy

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.343
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2020
Admission routes1
Has abstractyes

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