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Comparative study of direct mechanical thrombectomy and bridging therapy for acute anterior circulation large-artery occlusive stroke

2020· article· en· W3032103302 on OpenAlexaboutno aff
Haibing Ren, Huiqin Liu, Sisi Wang, Jianying Zhang, Wenjin Yang, Xiaohui Zhao, Ke Qing, Guodong Xiao, Yongjun Cao

Bibliographic record

VenueChinese Journal of Neuromedicine · 2020
Typearticle
Languageen
FieldNeuroscience
TopicNeurological Disease Mechanisms and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineThrombolysisModified Rankin ScaleStroke (engine)Bridging (networking)Glasgow Coma ScaleAnterior cerebral arterySurgeryCerebral infarctionArteryInternal medicineCardiologyMiddle cerebral arteryIschemic strokeMyocardial infarctionIschemia

Abstract

fetched live from OpenAlex

Objective To comparatively analyze the safety and efficacy of direct mechanical thrombectomy and bridging therapy for patients with acute anterior circulation large-artery occlusive stroke. Methods A total of 116 patients with acute anterior circulation large-artery occlusive stroke, admitted to our hospitals from October 2015 to March 2018, were chosen in our study; their clinical data were analyzed retrospectively. Among them, 63 patients accepted direct mechanical thrombectomy and 53 accepted bridging therapy. The preoperative baseline data and the diagnoses and treatments of the two groups were analyzed; the degrees of modified thrombolysis in cerebral infarction (mTICI), incidences of hemorrhage transformation and symptomatic intracranial hemorrhage, and modified Rankin scale (mRS) scores and mortality rate 90 d after operation were compared between the two groups. Results The preoperative Alberta stroke program early CT scale (ASPECTS) and Glasgow Coma Scale (GCS) scores of the direct mechanical thrombectomy group were significantly lower than those of the bridge therapy group (P 0.05). Conclusion The clinical efficacy and safety of direct mechanical thrombectomy and bridging therapy for patients with acute anterior circulation large-artery occlusive stroke are similar. Key words: Ischemic stroke; Anterior circulation; Mechanical thrombectomy; Intravenous thrombolysis; Bridging therapy

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.917
Threshold uncertainty score0.486

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.343
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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