The cognitive function of patients with early Parkinson's disease: a five-year follow-up
Bibliographic record
Abstract
Objective To investigate the changes in cognitive function in patients with early Parkinson's disease (PD) in a 5-year follow-up. Methods A total of 181 PD and 173 normal participants were recruited between January 2009 and January 2012 at the Department of Neurology, the Second Hospital of Jiaxing City.Regression analysis was used to evaluate the risk factors of cognitive impairment, and changes in subdomains of the Montreal Cognitive Assessment (MoCA) were compared annually with baseline data. Results Baseline clinical data were similar between the two groups.The level of cognitive impairment was positively correlated to the age of onset and the Hamilton Anxiety Scale (HAMD) (t=3.326, P 0.05). Seven subdomains of MoCA were attenuated, and four of them were significant different between the groups, including delayed recall, attention, abstraction task and orientation after the forth year of follow-up (all P 0.05). Conclusions Cognitive function of PD patients decreases significantly in some domains, such as delayed recall, attention, abstraction task and orientation after a five-year follow-up. Key words: Parkinson disease; Cognition disorders; Follow-up studies
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".