The cognitive function of patients with early Parkinson's disease: a five-year follow-up
Bibliographic record
Abstract
Objective To investigate the changes in cognitive function in patients with early Parkinson's disease (PD) in a 5-year follow-up. Methods A total of 181 PD and 173 normal participants were recruited between January 2009 and January 2012 at the Department of Neurology, the Second Hospital of Jiaxing City.Regression analysis was used to evaluate the risk factors of cognitive impairment, and changes in subdomains of the Montreal Cognitive Assessment (MoCA) were compared annually with baseline data. Results Baseline clinical data were similar between the two groups.The level of cognitive impairment was positively correlated to the age of onset and the Hamilton Anxiety Scale (HAMD) (t=3.326, P 0.05). Seven subdomains of MoCA were attenuated, and four of them were significant different between the groups, including delayed recall, attention, abstraction task and orientation after the forth year of follow-up (all P 0.05). Conclusions Cognitive function of PD patients decreases significantly in some domains, such as delayed recall, attention, abstraction task and orientation after a five-year follow-up. Key words: Parkinson disease; Cognition disorders; Follow-up studies
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".