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Comparative study of treatment of knee osteoarthritis with celecoxib and Yuanhu Zhitong capsule

2018· article· en· W3032808150 on OpenAlexaboutno aff
Zhaoming Cheng, Suqin Wang, Jianmin Kou, Luchang Zhuang, Kang Feng

Bibliographic record

Venue国际医药卫生导报 · 2018
Typearticle
Languageen
FieldMedicine
TopicInflammatory mediators and NSAID effects
Canadian institutionsnot available
Fundersnot available
KeywordsOsteoarthritisCelecoxibWOMACSodium hyaluronateMedicineCapsuleSurgeryInternal medicinePathologyAlternative medicine

Abstract

fetched live from OpenAlex

Objective To explore the clinical efficiency of Yuanhu Zhitong capsule in patients with osteoarthritis. Methods Sixty patients with osteoarthritis in Department of Orthopedics of our hospital from January 2015 to December 2016 were randomly divided into experimental group and control group. The experimental group was treated with Yuanhu Zhitong capsule and sodium hyaluronate, while the control group was treated with celecoxib and sodium hyaluronate. And the function of knee joint was assessed with the Western Ontario and McMaster Universities osteoarthritis index (WOMAC) and index severity of osteoarthritis (ISOA), the adverse reactions were recorded. Results The VAS score in the experimental group after treatment was (3.21±1.06), the WOMAC osteoarthritis index was (80.67±29.85), and index severity of osteoarthritis (ISOA) was (4.69±0.83), which were significantly lower than those in the control group [(5.39±2.03), (92.56±31.39), (5.22±0.57)] (P 0.05). Conclusion Yuanhu Zhitong capsule combined with sodium hyaluronate has obvious effect in patients with osteoarthritis, which can improve the score of joint function, relieve the pain of the patients, is another choice to treat the osteoarthritis patients with Chinese medicine. Key words: Yuanhu Zhitong capsule; Celecoxib; Osteoarthritis; Effect

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.277
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractyes

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