MétaCan
Menu
Back to cohort

Drug-attached magnetic nanoparticles: Locomotion control and in vivo biocompatibility

2020· article· en· W3039281284 on OpenAlexaff
Qian Xu, Ruixue Yin, Yuanxin Gu, Hongbo Zhang, Wenjun Zhang

Bibliographic record

VenueJournal of Physics Conference Series · 2020
Typearticle
Languageen
FieldMaterials Science
TopicNanoparticle-Based Drug Delivery
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsBiocompatibilityMagnetic nanoparticlesIn vivoFourier transform infrared spectroscopyNanoparticleDrug deliveryMaterials scienceNanotechnologyBiomedical engineeringDrugTargeted drug deliveryNuclear chemistryBiophysicsChemistryChemical engineeringPharmacologyMedicineBiotechnologyBiology

Abstract

fetched live from OpenAlex

Abstract Magnetic nanoparticles (MNPs) are playing an increasingly important role in the biomedical fields such as the diagnosis, treatment and monitoring of various diseases. Due to the unique properties of MNPs, MNPs with functionalized non-toxic surface coatings can be used for drug delivery in combination with therapeutic drugs or chemical molecules. A novel type of drug-attached magnetic nanoparticle was presented, where insulin was bound to magnetic Fe3O4 nanoparticles (MNPs-Insulin). It was particularly proposed for the future in vivo control to realize the targeted locomotion. The properties of the MNPs-Insulin were characterized by Fourier-transform infrared spectra (FTIR), thermo gravimetric analysis (TGA) and vibrating sample magnetometer (VSM) analysis. The ability of magnetic control was tested in the local motion control system in vitro. The good biocompatibility was certificated by Hematoxylin-eosin staining (HE) on mouse.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.000
Threshold uncertainty score0.001

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.236
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Physics Conference SeriesSame topicNanoparticle-Based Drug DeliveryFrench-language works237,207