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Population characteristics as important contextual factors in rheumatological trials: an exploratory meta-epidemiological study from an OMERACT Working Group

2020· review· en· W3039344762 on OpenAlexaff
Sabrina Mai Nielsen, Helene Storgaard, Torkell Ellingsen, Beverley Shea, George A. Wells, Vivian Welch, Daniel E. Furst, Maarten de Wit, Marieke Voshaar, Carsten Bogh Juhl, Maarten Boers, Reuben Escorpizo, Thasia Woodworth, Annelies Boonen, Henning Bliddal, Lyn March, Peter Tugwell, Robin Christensen

Bibliographic record

VenueAnnals of the Rheumatic Diseases · 2020
Typereview
Languageen
FieldMedicine
TopicRheumatoid Arthritis Research and Therapies
Canadian institutionsOttawa HospitalBruyèreUniversity of Ottawa
FundersOdense UniversitetshospitalOak Foundation
KeywordsMedicineEpidemiologyPopulationMeta-analysisPhysical therapyFamily medicineInternal medicineGerontologyEnvironmental health

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearchMeta-epidemiology (broad)
Domain: Methods · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Observationallow
gptMetaresearchMeta-epidemiology (narrow)Meta-epidemiology (broad)
Domain: Methods · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Systematic reviewhigh
models splitAgreement compares identical category sets and study designs across arms.

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.040
metaresearch head score (Gemma)0.077
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (broad)
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.990
Threshold uncertainty score0.212

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0400.077
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0100.031
Bibliometrics0.0030.004
Science and technology studies0.0010.001
Scholarly communication0.0050.002
Open science0.0020.003
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.434
GPT teacher head0.473
Teacher spread0.039 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

MetaresearchMeta-epidemiology (broad)Meta-epidemiology (narrow)

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designObservational · Systematic review
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2020
Admission routes1
Has abstractno

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