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Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells

2020· article· en· 347 citations· W3040208892 on OpenAlex· 10.1016/j.immuni.2020.06.002

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.033
GPT teacher head0.249
Teacher spread
0.216 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

tissue-resident memory T cells. Together, these findings define DC3s as a lineage of inflammatory DCs endowed with a strong potential to regulate tumor immunity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

The record

Venue
Immunity
Topic
Immunotherapy and Immune Responses
Field
Immunology and Microbiology
Canadian institutions
Funders
Fondo Nacional de Desarrollo Científico y TecnológicoGuy's and St Thomas' NHS Foundation TrustComisión Nacional de Investigación Científica y TecnológicaBiotechnology and Biological Sciences Research CouncilInstitut National Du CancerInstitut National de la Santé et de la Recherche MédicaleAgence Nationale de la RechercheNational Centre for the Replacement Refinement and Reduction of Animals in ResearchKing’s College LondonCancer Research UKNational Centre for the Replacement, Refinement and Reduction of Animals in ResearchRosetrees TrustNIHR Exeter Clinical Research FacilityCentre National de la Recherche ScientifiqueCNIBNational Institute for Health and Care ResearchInstitut CurieNIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer ResearchWorldwide Cancer Research
Keywords
BiologyCell biologyCD11cPriming (agriculture)CD8Dendritic cellCytotoxic T cellImmunologyCD163Homing (biology)AntigenIn vitroMacrophagePhenotype
Has abstract in OpenAlex
yes