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Record W3041117374

Parallel Adaptations to High Temperatures in the Archaean Eon

2010· article· en· W3041117374 on OpenAlexaff
Bastien Boussau, Samuel Blanquart, Anamaria Necşulea, Nicolas Lartillot, Manolo Gouy

Bibliographic record

VenueRePEc: Research Papers in Economics · 2010
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsUniversité de Montréal
Fundersnot available
KeywordsBiologyAncestorArchaeaMost recent common ancestorEvolutionary biologyThermophileGenomePhylogenetic treeExtremophileTree of life (biology)AbiogenesisPhylogeneticsArcheanGeneticsEcologyGenePaleontologyBacteriaGeography
DOInot available

Abstract

fetched live from OpenAlex

LUCA blows hot and cold There is a fascination about the quest to learn more about 'LUCA', the hypothetical last universal common ancestor from which all current living organisms are descended. Fossil evidence from the time, 3.5 to 3.8 billion years ago, is sparse and so LUCA hunters rely on indirect evidence for information on LUCA's biology and environment. Reconstructions of ancestral protein sequences based on genetic evidence from extant genomes pointed to a hot environment, and a thermophilic LUCA. But ribosomal RNA sequences were thought consistent with a cooler environment. A new 'molecular thermometer' method may have resolved this apparent discrepancy. The analysis of rRNA and protein sequences from hundreds of modern species using the latest mathematical models of molecular evolution suggests that there were two phases of environmental temperature change. What was to become LUCA was first mesophilic, living in waters at about 60°C, then adapted to higher temperatures, above 70°C, to produce a thermophilic common ancestor. As the oceans then cooled the Bacteria and Archaea–Eukaryota diversified.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.289
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

Explore more

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