Case of multiple myeloma with cutaneous involvement and aberrant CD3 expression
Bibliographic record
Abstract
SUMMARY A six‐year‐old golden retriever presented for a fast‐growing mass at the level of the left mandibular area. Cytological evaluation was consistent with an anaplastic round cell neoplasm. CT scan and abdominal ultrasound showed the presence of a large mass affecting the left mandibular salivary gland, several subcutaneous nodules and generalised intra‐abdominal lymphadenomegaly. The mandibular mass was surgically removed, and histopathology and immunohistochemistry were compatible with plasma cell tumour with aberrant CD3 expression. Complete staging led to the diagnosis of multiple myeloma with skin and salivary gland involvement. After receiving one dose of vincristine, the dog was started on melphalan/prednisolone protocol. After initial improvement, the dog showed signs of progressive disease and was euthanased 35 days after starting treatment due to severe clinical deterioration. Postmortem examination showed infiltration by neoplastic cells in several organs including the heart, the conjunctiva and some abdominal organs.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".