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Record W3044667119 · doi:10.1097/ftd.0000000000000792

Pharmacokinetic–Pharmacogenomic Model for Chinese Children Treated With Lamotrigine Also Applies for Mexican Children

2020· letter· en· W3044667119 on OpenAlexaff
José Eduardo Juárez‐Hernández, Michel Gutiérrez-Ceniceros, José Rodrigo González-Ramírez, Mara Medeiros-Domingo, Bruce Carleton, Colin J.D. Ross, Gilberto Castañeda‐Hernández

Bibliographic record

VenueTherapeutic Drug Monitoring · 2020
Typeletter
Languageen
FieldMedicine
TopicPharmacological Effects and Toxicity Studies
Canadian institutionsBC Children's HospitalUniversity of British Columbia
Fundersnot available
KeywordsLamotrigineHumanitiesMedicineArtPsychiatryEpilepsy

Abstract

fetched live from OpenAlex

Juárez-Hernández, José Eduardo MD, MSc*,†,‡; Gutiérrez-Ceniceros, Michel MD§; González-Ramírez, José Rodrigo PhD*; Medeiros, Mara MD, PhD¶,‖; Carleton, Bruce PharmD†,‡,*,*; Ross, Colin PhD‡,†,†; Castañeda-Hernández, Gilberto PhD* Author Information

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.316
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.323
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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