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Record W3045444247 · doi:10.5539/jfr.v9n5p14

Efficacy of the Aqueous Extracts of Justicia Galeopsis Leaves on the Improvement of Hematological Parameters in Anemic Rats

2020· article· en· W3045444247 on OpenAlexvenueno aff
Ahou Léticia Loukou, Moussa Gbogbo, Raissa Sandy Assi, Louise Atchibri-Anin, Kouakou Brou

Bibliographic record

VenueJournal of Food Research · 2020
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicDrug-Induced Hepatotoxicity and Protection
Canadian institutionsnot available
Fundersnot available
KeywordsHematocritHemoglobinAnemiaDistilled waterPhenylhydrazineAqueous extractKidneyMedicineBody weightSpleenTraditional medicineChemistryAnimal sciencePharmacologyInternal medicineBiologyChromatography

Abstract

fetched live from OpenAlex

Antianemc potential of aqueous of Justicia galeopsis leaves was studied using Wistar Albino rats after induction of anemia by phenylhydrazine hydrochloride. Forty rats (20 male and 20 female) subdivided into five groups of eight rats were used. There was a group as control (not anemic) and four other anemic groups which had received by gavage respectively 1 ml/kg of distilled water, 1 ml/kg of body weight of Vitafer (reference drug commonly used to treat anemia), 100 mg/kg of body weight of extract of J. galeopsis leaves cooked during 30 min and 30 mg/kg of body weight of extract of J. galeopsis leaves cooked during 45 min. Hematological parameters (red blood cells, hemoglobin and hematocrit) were analyzed as indices of anemia and the weights of specific organs (liver, spleen and kidney) were evaluated. The results of this investigation had showed that aqueous extract of J. galeopsis leaves cooked improved red blood cells, hemoglobin and hematocrit levels. These extracts were not toxic for liver, spleen and kidney. The administration of 100 mg/kg/day of extract of leaves cooked leaves during 30 min promotes a better recovery rate of the number of red blood cells (94.80 %), hemoglobin level (159.53 %) and hematocrit (117.72 %) than Vitafer and the extract of leaves cooked for 45 min. This is suggestive that aqueous extracts of Justicia galeopsis leaves cooked during 30 min may be exploited during 2 weeks in the treatment of anemia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.453
GPT teacher head0.492
Teacher spread0.039 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2020
Admission routes1
Has abstractyes

Explore more

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