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Record W3046436160 · doi:10.1142/11971#t=toc

Genes, Germs And Medicine: The Life Of Joshua Lederberg

2021· book· en· W3046436160 on OpenAlexaff
Jan Sapp

Bibliographic record

Venuenot available
Typebook
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRace, Genetics, and Society
Canadian institutionsYork University
Fundersnot available
KeywordsPhilosophyBiology

Abstract

fetched live from OpenAlex

"Genes, Germs and Medicine explores the development of modern biomedical science in the United States through the life of one of the Twentieth Century's most influential scientists. Joshua Lederberg was a scientific renaissance man. He and his collaborators founded the field of bacterial genetics, and he was awarded the Nobel Prize at the age of 33 (the second youngest in history). He helped to lay the foundations for genetic engineering, made fundamental revisions to immunological and evolutionary theory, and developed medical genetics. He initiated the search for extraterrestrial microbial life, developed artificial intelligence, and was a visionary of the Digital Age. Lederberg coined some of the central terms of modern biology: plasmid, transduction, exobiology, euphenics and microbiome. A complex humanist who spoke out for social justice, Lederberg confronted racism, and denied a gene-centered view of humans. Pondering our social evolution outside of nature, he forewarned of the complex ethical issues arising from bioengineering. He sounded the alarm about coming pandemics at a time when few would listen, and warned of the peril of biowarfare and strove to prevent it. Lederberg was a man with a deep sense of social and intellectual responsibility, a trusted advisor to eight presidential administrations"--Publisher's website

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.167
Threshold uncertainty score0.660

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.243
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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