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Record W3080798331 · doi:10.1002/mds3.10119

Application of bile acids for biomedical devices and sensors

2020· article· en· W3080798331 on OpenAlexafffund
Kayla Baker, Rebecca Sikkema, Igor Zhitomirsky

Bibliographic record

VenueMedical Devices & Sensors · 2020
Typearticle
Languageen
FieldEngineering
TopicElectrophoretic Deposition in Materials Science
Canadian institutionsMcMaster University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsNanotechnologySurface modificationBiocompatibilityMaterials scienceBiosensorDrug deliveryBiocompatible materialPolymerCarbon nanotubeChemistryBiomedical engineering

Abstract

fetched live from OpenAlex

Abstract The objective of this mini‐review is to describe the recent advances and applications of bile acids (BAs) for manufacturing biomedical devices and sensors. The biological origin and unique multifunctional properties of BAs are key factors for novel biomedical applications. BAs are used for solubilization of drugs and the development of advanced devices for controlled drug delivery. BAs outperform many commercial dispersants in the dispersion of carbon nanotubes and hydrophobic polymers. They also exhibit unique gel‐forming and film‐forming properties, which are used for the development of biosensors and functionalization of implant materials. Especially important is the possibility of bile acid gel synthesis for controlled release of drugs and other functional molecules. Electrodeposition of BAs films and composites is emerging as a new area of technological interest. The discovery of BAs mediating the biomineralization phenomena allows the development of biomedical implants with enhanced bioactivity and biocompatibility. Bile acids are used as efficient biocompatible reducing and capping agents for the synthesis of inorganic particles and their functionalization for application in biosensors and antimicrobial coatings. The progress in the modification of biopolymers with BAs and development of BAs derivatives paves the way for the fabrication of advanced implants and sensors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.230
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2020
Admission routes2
Has abstractyes

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