<i>Letter to the Editor:</i> Possible Drug–Drug Interactions Between Cannabinoids and Candidate COVID-19 Drugs
Bibliographic record
Abstract
Cannabis and Cannabinoid ResearchVol. 5, No. 4 Letters to the EditorLetter to the Editor: Possible Drug–Drug Interactions Between Cannabinoids and Candidate COVID-19 DrugsM. Hunter Land, Laura MacNair, Brian F. Thomas, Erica N. Peters, and Marcel O. Bonn-MillerM. Hunter LandCanopy Growth Corporation, Smiths Falls, Ontario, Canada.Search for more papers by this author, Laura MacNairCanopy Growth Corporation, Smiths Falls, Ontario, Canada.Search for more papers by this author, Brian F. ThomasCanopy Growth Corporation, Smiths Falls, Ontario, Canada.Search for more papers by this author, Erica N. PetersCanopy Growth Corporation, Smiths Falls, Ontario, Canada.Search for more papers by this author, and Marcel O. Bonn-Miller*Address correspondence to: Marcel O. Bonn-Miller, PhD, Canopy Growth Corporation, 1 Hershey Drive, Smiths Falls K7A 0A8, Ontario, Canada E-mail Address: [email protected]Canopy Growth Corporation, Smiths Falls, Ontario, Canada.University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.Search for more papers by this authorPublished Online:15 Dec 2020https://doi.org/10.1089/can.2020.0054AboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookXLinked InRedditEmail View articleFiguresReferencesRelatedDetailsCited byThe Potential of Cannabidiol for Acute Respiratory Distress Syndrome in COVID-19Current Pharmaceutical Design, Vol. 29, No. 29A Scoping Review on the Medical and Recreational Use of Cannabis During the COVID-19 Pandemic Wendy Wing-Yee Chong, Zeynep Ilgaz Acar, Meghan Lee West, and Francis Wong12 October 2022 | Cannabis and Cannabinoid Research, Vol. 7, No. 5Implications of Cannabis and Cannabinoid Use in COVID-19: Scoping Review1 January 2022 | Revista Brasileira de Enfermagem, Vol. 75, No. suppl 1Cannabis/Cannabinoids for Treating COVID-19 Associated Neuropsychiatric Complications16 October 2021 | Journal of Neuroimmune Pharmacology, Vol. 16, No. 4Commentary: Use of Cannabinoids to Treat Acute Respiratory Distress Syndrome and Cytokine Storm Associated With Coronavirus Disease-201912 April 2021 | Frontiers in Pharmacology, Vol. 12 Volume 5Issue 4Dec 2020 InformationCopyright 2020, Mary Ann Liebert, Inc., publishersTo cite this article:M. Hunter Land, Laura MacNair, Brian F. Thomas, Erica N. Peters, and Marcel O. Bonn-Miller.Letter to the Editor: Possible Drug–Drug Interactions Between Cannabinoids and Candidate COVID-19 Drugs.Cannabis and Cannabinoid Research.Dec 2020.340-343.http://doi.org/10.1089/can.2020.0054Published in Volume: 5 Issue 4: December 15, 2020Online Ahead of Print:August 26, 2020PDF download
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.003 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.003 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".