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Record W3081385004 · doi:10.1101/2020.08.25.266395

Occurrence of extended spectrum β-lactamase and AmpC-producing <i>Escherichia coli</i> in retail meat products from the Maritime Provinces, Canada

2020· preprint· en· W3081385004 on OpenAlexafffundabout
Babafela Awosile, Jessica Eisnor, Matthew E. Saab, Luke C. Heider, J. Trenton McClure

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2020
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAntibiotic Resistance in Bacteria
Canadian institutionsUniversity of Prince Edward Island
FundersAtlantic Veterinary College
KeywordsEscherichia coliMultiplex polymerase chain reactionCephalosporinBiologyMicrobiologyAntibiotic resistancePolymerase chain reactionAntimicrobialVeterinary medicineGeneAntibioticsMedicineGenetics

Abstract

fetched live from OpenAlex

Abstract This study was conducted to determine the occurrence of antimicrobial resistance to the extended-spectrum cephalosporins (ESC) in Escherichia coli isolates recovered from retail meat products collected in the Maritime Provinces of Canada using both selective and traditional culture methods, and genotypically using multiplex polymerase chain reactions. ESC-R E. coli was detected in 33/559 (5.9%) samples using the traditional culture compared to 151/557 (27.1%) samples using the selective culture method. The recovery of ESC-R E. coli isolates was more common in poultry compared to beef and pork (P<0.001). Multi-drug resistance, ESBL, and AmpC phenotypes were more common in chicken-derived isolates than other retail meat products (P<0.001). From the 98 isolates selected, 76 (77.6%) isolates were positive for either ESBL and AmpC β-lactamases or both. Among the 76 isolates, bla CMY-2 (78.9%), bla CTXM (46.1%), bla TEM (21.1%), and bla SHV (1.3%) were detected. Among the bla CTXM -producing isolates; bla CTXM-1 , bla CTXM-2 , and bla CTXM-9 phylogenetic groups were detected. β-lactamase genes were detected more in chicken-derived isolates compared to other meat types (P<0.01). This study demonstrated the occurrence of ESBL and AmpC resistance genes in retail meat products in Maritime Provinces of Canada. Also, selective culture significantly improved the recovery of ESC-R E. coli isolates from retail meat samples.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.051
Threshold uncertainty score0.102

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.195
Teacher spread0.185 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes3
Has abstractyes

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