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Record W3082704660 · doi:10.1016/j.jacl.2020.08.009

Bempedoic acid safety analysis: Pooled data from four phase 3 clinical trials

2020· article· en· W3082704660 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueJournal of clinical lipidology · 2020
Typearticle
Languageen
FieldMedicine
TopicLipoproteins and Cardiovascular Health
Canadian institutionsUniversity of British ColumbiaUniversity of TorontoSt. Michael's Hospital
FundersAbbott VascularNational Institutes of HealthNovo NordiskMedicines CompanyValeant Pharmaceuticals InternationalNovartisEli Lilly and CompanyAstraZenecaPfizerNIHR Imperial Biomedical Research CentreAmgenBoehringer IngelheimKowa CompanyMeso Scale DiagnosticsSanofiEsperion TherapeuticsMerckAmerican Heart AssociationAmerican Diabetes Association
KeywordsMedicinePlaceboInternal medicineDiscontinuationGastroenterologyAdverse effectmyalgiaUric acid

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.055
metaresearch head score (Gemma)0.093
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.627
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0550.093
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0070.005
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.549
GPT teacher head0.566
Teacher spread0.016 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it