Commentary: Femoral artery homograft for coronary artery plasty—will it withstand the test of time?
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Central MessageFemoral artery homograft has been successfully used for coronary artery plasty in this case report with short-term follow-up, but time-tested verification of its utility is still required.See Article page 232. Femoral artery homograft has been successfully used for coronary artery plasty in this case report with short-term follow-up, but time-tested verification of its utility is still required. See Article page 232. In this issue of JTCVS Techniques, Mosca and colleagues1Mosca R. Chen D. Halpern D. Ma C. Feinberg J. Bhatla P. et al.Femoral artery homograft for coronary artery plasty following arterial switch operation.J Thorac Cardiovasc Surg Tech. 2020; 4: 232-234Google Scholar present a case report describing the use of femoral artery homograft for stenosis of a single coronary artery system following the arterial switch procedure. While numerous options were considered including bypass grafting and unroofing of the adjacent segment, ultimately the authors proceeded with left main coronary artery patch plasty due to the young patient age of 22 years and the specific anatomy of the lesion. They augmented the coronary artery using femoral artery homograft. At 7 months of follow-up, this patient remained asymptomatic with a coronary computed tomographic angiogram demonstrating a widely patent left main coronary artery. A well-understood complication of any coronary artery surgery, especially of infants undergoing the arterial switch operation, is ostial stenosis presenting either in the immediate postoperative period or during late follow-up. A primary solution in this scenario is patch plasty, which consists of patching across the area of stenosis. Within this report, the authors present the novel use of femoral artery homograft. They suggest that it is a suitable choice due to its natural curvature and tissue properties, such as having an endothelial lining that may make it less thrombogenic compared with other alternatives and its hemostatic properties. As the authors mention, multiple different types of patch materials have been described in the literature for coronary artery patch plasty, including native and treated autologous pericardium, saphenous vein, bovine pericardium, and pulmonary homograft.2Li J. Lai H. Zheng J. Guo C. Gu J. Wang C. Patch repair of anomalous origin of the left main coronary artery from the anterior aortic sinus.Ann Thorac Surg. 2014; 97: e59-e61Abstract Full Text Full Text PDF PubMed Scopus (1) Google Scholar, 3Dion R. Elias B. El Khoury G. Noirhomme P. Verhelst R. Hanet C. Surgical angioplasty of the left main coronary artery.Eur J Cardiothorac Surg. 1997; 11: 857-864Crossref PubMed Scopus (43) Google Scholar, 4Karl T.R. Provenzano S.C. Nunn G.R. Anomalous aortic origin of a coronary artery: a universally applicable surgical strategy.Cardiol Young. 2010; 20: 44-49Crossref PubMed Scopus (12) Google Scholar, 5Thistlethwaite P.A. Madani M.M. Kriett J.M. Milhoan K. Jamieson S.W. Surgical management of congenital obstruction of the left main coronary artery with supravalvular aortic stenosis.J Thorac Cardiovasc Surg. 2000; 120: 1040-1046Abstract Full Text Full Text PDF PubMed Scopus (43) Google Scholar, 6Kaczorowski D.J. Sathanandam S. Ravishankar C. Gillespie M.J. Montenegro L.M. Gruber P.J. et al.Coronary ostioplasty for congenital atresia of the left main coronary artery ostium.Ann Thorac Surg. 2012; 94: 1307-1310Abstract Full Text Full Text PDF PubMed Scopus (22) Google Scholar These patch materials each have their own inherent characteristics and limitations. It is well known that autologous pericardium often retracts, thickens, and calcifies over time, and that bovine pericardium too calcifies.7Neethling W.M. Strange G. Firth L. Smit F.E. Evaluation of a tissue-engineered bovine pericardial patch in paediatric patients with congenital cardiac anomalies: initial experience with the ADAPT-treated CardioCel(R) patch.Interact Cardiovasc Thorac Surg. 2013; 17: 698-702Crossref PubMed Scopus (51) Google Scholar The primary limitation that remains, however, is that none have been shown to be time-tested and true, including that of femoral artery homograft. The majority of studies, such as the ones referenced herein are case series, and most have little or no follow-up of patch durability. It should also be emphasized that it is just as important to have a technically sound repair. This is important, not only for the initial procedure, but for the reoperation. With respect to the initial procedure, it is important to understand and evaluate the factors that may have led to stenosis, most importantly the anatomy of the vessels in relation to the commissure, the ostial morphology, and the technique used for coronary artery transfer. With respect to the subsequent repair, coronary artery patch plasty must be performed while ensuring that the incision is appropriately beyond the stenosis and that the patch geometry prevents turbulent flow and kinking. However, resolving the debate regarding which patch material is superior is a must and should be done through careful scientific evaluation of a larger number of patients with a longer period of follow-up to determine which material will withstand the test of time. Femoral artery homograft for coronary artery plasty following arterial switch operationJTCVS TechniquesVol. 4PreviewA 22-year-old young man who previously underwent an arterial switch operation (ASO) as an infant for d-transposition of the great arteries with single right coronary artery presented with exertional angina. Echocardiogram demonstrated good repair with preserved biventricular contractility. Stress test was positive for ischemic changes. Cardiac catheterization and coronary computed tomography angiogram (CTA) revealed a single coronary artery that arose from the right facing sinus and bifurcated into a widely patent and dominant right coronary artery and a left main coronary artery (LMCA) that was severely stenosed at its origin (Figure 1, A). Full-Text PDF Open Access
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it