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Record W3089911868 · doi:10.1212/wnl.0000000000010978

Opsoclonus Myoclonus Ataxia Syndrome in the Setting of COVID-19 Infection

2020· article· en· W3089911868 on OpenAlexaff
Priyank Bharatkumar Shah, Soaham Desai

Bibliographic record

VenueNeurology · 2020
Typearticle
Languageen
FieldMedicine
TopicAutoimmune Neurological Disorders and Treatments
Canadian institutionsPrivy Council Office
Fundersnot available
KeywordsMyoclonusOpsoclonusCoronavirus disease 2019 (COVID-19)MedicineAtaxiaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakVirologyPediatricsPathologyAnesthesiaBiologyPsychiatryGeneticsInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

A middle-aged man presented with imbalance and involuntary jerky movements of the body 3 weeks after initial recovery from coronavirus disease 2019 (COVID-19) lung infection, diagnosed by positive high-resolution CT thorax (COVID Reporting and Data System 5) and reverse transcription PCR (RT-PCR) from nasal swab.He had opsoclonus, cortical myoclonus, and symmetric cerebellar ataxia of speech, limbs, trunk, and gait on examination 1 (video 1).His MRI brain with contrast, CSF examination, HIV, Venereal Disease Research Laboratory, autoimmune, and paraneoplastic panel (including anti-GAD, antinuclear antibodies, antineutrophil cytoplasmic antibodies, anti-Hu, anti-Yo, anti-Ri, anti-amphiphysin, anti-PNAM2-Ma2/Ta antibodies), metabolic functions (hemogram, hematocrit, glucose, thyroid, renal, hepatic functions, electrolytes, serum and urine osmolality), and repeat nasal COVID-19 RT-PCR were normal.He recovered after treatment consisting of IV methylprednisolone (1 g/d), sodium valproate (20 mg/kg/d), clonazepam (2 mg/d), and levetiracetam (2 g/d) in 1 week (video 2).Our case adds to the increasing list of novel neurologic manifestations occurring in the setting of 3

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0030.002
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.290
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations49
Published2020
Admission routes1
Has abstractyes

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