MétaCan
Menu
Back to cohort
Record W3093940905 · doi:10.1128/jvi.01580-20

Country Level Diversity of the HIV-1 Pandemic between 1990 and 2015

2020· review· en· W3093940905 on OpenAlexfundno aff
Joris Hemelaar, Shanghavie Loganathan, Ramyiadarsini Elangovan, Jason Yun, Leslie Dickson-Tetteh, Shona Kirtley

Bibliographic record

VenueJournal of Virology · 2020
Typereview
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsnot available
FundersInstituto Nacional do Câncer, Ministério da SaúdeMedical Research CouncilSchool of Medicine, Vanderbilt UniversityCenters for Disease Control and PreventionRobert Koch InstitutUniversity of North Carolina at Chapel HillFundação Oswaldo CruzUniversiti MalayaMahidol UniversityKarolinska InstitutetKU LeuvenUniversidad Nacional Autonoma de HondurasKoch Institute for Integrative Cancer Research, Massachusetts Institute of TechnologyStichting HIV MonitoringUniversity College LondonWorld Health OrganizationSeoul National UniversityEmory UniversityUniversidade Federal do Rio de JaneiroUniversité de BordeauxFaculty of Medicine Siriraj Hospital, Mahidol UniversitySchool of Medicine, Emory UniversitySchool of Medicine, New York UniversityUniversiteit van AmsterdamLondon School of Hygiene and Tropical MedicineLos Alamos National LaboratoryUniversity of WashingtonChinese Center for Disease Control and PreventionYork UniversityUniversity of PennsylvaniaUniversité de MontpellierVanderbilt University
KeywordsPandemicBiologyChinaHuman immunodeficiency virus (HIV)Diversity (politics)VirologyCentral asiaCoronavirus disease 2019 (COVID-19)GeographyInfectious disease (medical specialty)DiseasePolitical scienceMedicine

Abstract

fetched live from OpenAlex

This is the first study to analyze global country level HIV-1 diversity from 1990 to 2015. We found extremely wide variation in complexity of country level HIV diversity around the world. Central African countries have the most diverse HIV epidemics. The number of distinct HIV-1 subtypes and recombinants was greatest in Western Europe and North America. The proportion of HIV-1 infections due to recombinants was highest in South-East Asia, China, and West and Central Africa. The highest proportions of URFs were found in Myanmar, Republic of the Congo, and Argentina. Our study provides epidemiological evidence that the HIV pandemic is diversifying at country level and highlights the increasing challenge to HIV vaccine development and diagnostic, drug resistance, and viral load assays.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.767
Threshold uncertainty score0.486

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.142
GPT teacher head0.412
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations42
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueJournal of VirologySame topicHIV/AIDS Research and InterventionsFrench-language works237,207